Effective Care Research Unit, Eastern Cape Department of Health, University of the Witwatersrand, University of Fort Hare, South Africa.
Early Hum Dev. 2009 Oct;85(10):611-5. doi: 10.1016/j.earlhumdev.2009.09.010. Epub 2009 Oct 12.
Meconium-stained amniotic fluid is a common occurrence which places the mother at risk of escalating obstetric interventions, and the baby at risk of meconium aspiration syndrome.
The Cochrane Library was searched for interventions related to care before delivery with useful evidence on the outcomes 'meconium-stained amniotic fluid' and 'meconium aspiration syndrome'.
Curtailment of post-term pregnancy reduces the occurrence of meconium-stained amniotic fluid, and meconium aspiration syndrome. Uterine stimulants, particularly misoprostol, are associated with occurrence of meconium-stained amniotic fluid. Amniotomy during labour may be a risk factor for meconium aspiration syndrome. There is little research evidence on the benefits or otherwise of obstetric interventions such as expedited delivery for meconium-stained liquor without other evidence of fetal distress. Amnioinfusion for meconium-stained amniotic fluid improves neonatal outcome only in settings with limited peripartum surveillance. There is insufficient evidence to support the use of amnioinfusion for meconium-stained liquor in settings with adequate peripartum surveillance.
胎粪污染羊水是一种常见现象，使母亲面临产科干预升级的风险，婴儿则面临胎粪吸入综合征的风险。
检索 Cochrane 图书馆中与分娩前护理干预相关的文献，这些文献提供了有关“胎粪污染羊水”和“胎粪吸入综合征”结局的有用证据。
缩短过期妊娠可降低胎粪污染羊水和胎粪吸入综合征的发生。子宫收缩剂，特别是米索前列醇，与胎粪污染羊水的发生有关。分娩时行人工破膜可能是胎粪吸入综合征的一个危险因素。对于没有其他胎儿窘迫证据的胎粪污染羊水，加速分娩等产科干预的益处或其他方面的研究证据很少。对于围产期监测有限的情况，羊膜内输注胎粪污染羊水可改善新生儿结局。在围产期监测充分的情况下，羊膜内输注胎粪污染羊水的证据不足。
