Neuner Tanja, Mehlsteibl Dorothea, Hübner-Liebermann Bettina, Schmid Rita, Schielein Tanja, Hausner Helmut, Hajak Göran, Spiessl Hermann
Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie der Universität am Bezirksklinikum Regensburg, Regensburg.
Psychiatr Prax. 2010 Apr;37(3):119-26. doi: 10.1055/s-0029-1223349. Epub 2009 Oct 12.
This psychological autopsy study investigates suicide risk factors of schizophrenic and depressive inpatients.
67 potential risk factors of inpatient suicide were identified by means of literature research and caregiver interviews of schizophrenic and depressive suicidents (1995-2004). The medical records of the suicidents (n = 20) were analysed in respect to the identified risk factors and compared to their respective control group of non-suicidents (n = 20) which was matched by diagnosis, gender, age, year / month of admission and ward. Univariate and multivariate statistical analyses were performed.
In comparison to their respective control group schizophrenic (n = 11) and depressive suicidents (n = 9) differed clearly by their risk profile. Suffering from side effects of medication was found to be a predictor of suicide for schizophrenic inpatients.
Psychological autopsy studies are indispensable for the construction of diagnosis-specific risk profiles. Reduction of side effects of medication seems to play a larger role in suicide prevention for schizophrenic inpatients than previously assumed.
本心理解剖学研究调查精神分裂症和抑郁症住院患者的自杀风险因素。
通过文献研究以及对1995年至2004年间精神分裂症和抑郁症自杀患者的照料者访谈，确定了67个住院患者自杀的潜在风险因素。对自杀患者（n = 20）的病历就已确定的风险因素进行分析，并与各自的非自杀对照组（n = 20）进行比较，非自杀对照组在诊断、性别、年龄、入院年份/月份和病房方面进行了匹配。进行了单变量和多变量统计分析。
与各自的对照组相比，精神分裂症自杀患者（n = 11）和抑郁症自杀患者（n = 9）在风险特征上有明显差异。发现药物副作用是精神分裂症住院患者自杀的一个预测因素。
心理解剖学研究对于构建特定诊断的风险概况必不可少。减少药物副作用在精神分裂症住院患者的自杀预防中似乎比以前认为的发挥更大的作用。
