Crowley Michael J, Wu Jia, McCarty Erika R, David Daryn H, Bailey Christopher A, Mayes Linda C
Yale Child Study Center, Yale School of Medicine, New Haven, Connecticut 06473, USA.
Neuroreport. 2009 Nov 25;20(17):1518-22. doi: 10.1097/WNR.0b013e328330377a.
We studied time-based neural activity with event-related potentials (ERPs) in young adults during a computer-simulated ball-toss game. Experiencing fair play initially, participants were ultimately excluded by other players. Dense-array ERPs showed time-dependent associations between slow-wave activity (580-900 ms) in left prefrontal/medial frontal cortical regions for exclusion events and self-reported distress. More subtle 'micro-rejections' during fair play showed a similar distress to ERP association (420-580 ms). In both cases, greater positive amplitude neural activity was associated with less post-exclusion distress. Findings suggest that rapidly occurring neural responses to social exclusion events are linked to individual differences in ostracism-related distress. Relations emerged even during fair play, providing a window into the neural basis of more subtle social-cognitive perceptual processes.
我们在一项计算机模拟抛球游戏中，利用事件相关电位（ERP）研究了年轻人基于时间的神经活动。参与者最初体验到公平游戏，但最终被其他玩家排除在外。密集阵列ERP显示，在左前额叶/内侧额叶皮质区域，排除事件的慢波活动（580 - 900毫秒）与自我报告的痛苦之间存在时间依赖性关联。公平游戏期间更微妙的“微排斥”显示出与ERP关联（420 - 580毫秒）类似的痛苦。在这两种情况下，更大的正振幅神经活动与排除后较少的痛苦相关。研究结果表明，对社会排斥事件的快速神经反应与排斥相关痛苦的个体差异有关。即使在公平游戏期间也出现了这种关系，为更微妙的社会认知感知过程的神经基础提供了一个窗口。
