Department of Medicine/Division of Nephrology, New York Medical College/Westchester Medical Center, Valhalla, NY 10595, USA.
Cardiol Rev. 2009 Nov-Dec;17(6):263-9. doi: 10.1097/CRD.0b013e3181bc359d.
Contrast-induced nephropathy, also referred to as contrast-induced acute kidney injury (CIAKI), is among the most common causes of AKI, especially in patients with underlying chronic kidney disease. In addition to the increased cost engendered by the development of CIAKI, several studies have suggested the occurrence of AKI after cardiac procedures is associated with an increase in both morbidity and mortality. This increase in morbidity and mortality occurs after both intravenous and intra-arterial studies. This review focuses on relevant proposed pathophysiological mechanisms, risk factors, and current prophylactic strategies, which may reduce the incidence of CIAKI during cardiac angiographic imaging studies.
对比剂肾病,也称为对比剂诱导的急性肾损伤(CIAKI),是急性肾损伤(AKI)最常见的原因之一,尤其是在患有基础慢性肾脏病的患者中。除了 CIAKI 发展所带来的成本增加外,多项研究表明,心脏手术后 AKI 的发生与发病率和死亡率的增加有关。这种发病率和死亡率的增加发生在静脉内和动脉内研究之后。本综述重点介绍了相关的病理生理学机制、危险因素和当前的预防策略,这些策略可能会降低心脏血管造影成像研究期间 CIAKI 的发生率。