Some pharmacological properties of perhydro-1,4-thiazepine and perhydro-1,2,5-dithiazepine derivatives.
作者信息
Strzelczyk M, Matyjewska H, Strózyński H
机构信息
Department of Biochemistry, Pharmacology and Biology, Military Medical Academy, Lódź, Poland.
出版信息
Pol J Pharmacol Pharm. 1990 Jul-Aug;42(4):377-85.
PMID:1982963
Abstract
Some newly synthesized perhydro-1,2,5-dithiazepine derivatives have antihistaminic, anticholinergic and spasmolytic properties. One perhydro-1,4-thiazepine derivative, compound 3, produces also a weak local anesthetic effect. The activity of the investigated compounds is lower than that of reference compounds; diphenhydramine, antazoline and papaverine.
摘要
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