Antoniades Demetrios, Apostolakis Stavros, Tzoras Spiros, Lazaridis Kyriakos
Department of Cardiology, Army Veterans Hospital Athens Greece.
Cases J. 2009 Jul 2;2:6797. doi: 10.4076/1757-1626-2-6797.
Coronary artery dissections with or without rupture is a rare but well-recognized complication of coronary angiography with a high morbidity and mortality rate.
We present a rare case of right coronary artery dissection distal to a totally occluded vessel. The vessel dissected during the second injection of contrast agent without any direct mechanical manipulation (catheter or guide-wire induced). Hopefully the dissection had no clinical consequences and the patient was discharged after 48 hour intensive monitoring.
We believe that the contrast agent that was forced in the proximal part of the RCA increased through the anastomotic branches the sheer stress on the diseased endothelium of the distal artery causing it to dissect. It is an instructive -not previously described- phenomenon that underscores that atherosclerotic tissue is unpredictable and should be treated with extreme caution.
伴有或不伴有破裂的冠状动脉夹层是冠状动脉造影罕见但已被充分认识的并发症,其发病率和死亡率很高。
我们报告一例罕见的右冠状动脉在完全闭塞血管远端发生夹层的病例。在第二次注射造影剂时血管发生夹层,未进行任何直接的机械操作(导管或导丝所致)。所幸该夹层未产生临床后果,患者在经过48小时的密切监测后出院。
我们认为,注入右冠状动脉近端的造影剂通过吻合支增加了远端动脉病变内皮上的切应力,从而导致夹层形成。这是一种有指导意义的——此前未被描述过的——现象,强调了动脉粥样硬化组织不可预测,治疗时应极其谨慎。