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大面积肠缺血,口服避孕药引起的肠系膜静脉血栓形成的罕见并发症:一例报告并文献复习

Massive intestinal ischemia, a rare complication of oral contraceptive-induced mesenteric venous thrombosis: a case report and review of literature.

作者信息

Efremidou Eleni I, Kouklakis George, Tsirogianni Olga, Courcoutsakis Nikolaos, Manolas Konstantinos J, Liratzopoulos Nikolaos

机构信息

First Surgical Department, University Hospital of Alexandroupolis, Democritus University of Thrace, Greece.

出版信息

Cases J. 2009 May 18;2:7416. doi: 10.1186/1757-1626-2-7416.

Abstract

Intestinal necrosis and perforation is a clinical and pathological presentation of the infrequently seen mesenteric venous thrombosis in women using oral contraceptives.We report a case of a previously healthy 31-year-old female patient, who presented with a 3-day history of abdominal pain.Although chest and abdomen radiographs showed small bowel obstruction, conservative treatment failed and the patient developed peritonism. Contrast-enhanced Tomography of the abdomen revealed free air associated with dilated and thickened small bowel. A laparotomy was performed and segmental resection of both small and large bowel was required. The pathological examination showed intestinal ischemia and mesenteric venous thrombosis. There were no further predisposing factors and mesenteric venous thrombosis was ascribed to oral contraceptives.

摘要

肠坏死和穿孔是使用口服避孕药的女性中罕见的肠系膜静脉血栓形成的临床和病理表现。我们报告一例31岁既往健康的女性患者,她有3天的腹痛病史。尽管胸部和腹部X线片显示小肠梗阻,但保守治疗失败,患者出现腹膜炎。腹部增强CT显示有游离气体,伴有小肠扩张和增厚。进行了剖腹手术,需要对小肠和大肠进行节段性切除。病理检查显示肠缺血和肠系膜静脉血栓形成。没有其他诱发因素,肠系膜静脉血栓形成归因于口服避孕药。

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