Georgin-Lavialle Sophie, Darmon Michael, Galicier Lionel, Fysekidis Marinos, Azoulay Elie
J Med Case Rep. 2009 May 12;3:7253. doi: 10.1186/1752-1947-3-7253.
The occurrence of an intravascular lymphoma with severe pulmonary involvement mimicking pulmonary embolism is described.
A 38-year-old man was referred to our intensive care unit with acute respiratory failure and long lasting fever. Appropriate investigations failed to demonstrate any bacterial, viral, parasitic or mycobacterial infection. A chest computed tomography scan ruled out any proximal or sub-segmental pulmonary embolism but the ventilation/perfusion lung scan concluded that there was a high probability of pulmonary embolism. The cutaneous biopsy pathology diagnosed intravascular lymphoma.
Intravascular lymphoma is a rare disease characterized by exclusive or predominant growth of neoplastic cells within the lumina of small blood vessels. Lung involvement seems to be common, but predominant lung presentation of this disease is rare. In our patient, urgent chemotherapy, along with adequate supportive care allowed complete recovery.
本文描述了一例血管内淋巴瘤伴严重肺部受累、酷似肺栓塞的病例。
一名38岁男性因急性呼吸衰竭和持续发热被收入我们的重症监护病房。适当的检查未能发现任何细菌、病毒、寄生虫或分枝杆菌感染。胸部计算机断层扫描排除了任何近端或亚段肺栓塞，但通气/灌注肺扫描结果显示肺栓塞的可能性很大。皮肤活检病理诊断为血管内淋巴瘤。
血管内淋巴瘤是一种罕见疾病，其特征是肿瘤细胞在小血管腔内排他性或主要生长。肺部受累似乎很常见，但以肺部表现为主的这种疾病很少见。在我们的患者中，紧急化疗加上充分的支持治疗使患者完全康复。
