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一名曾因喉癌接受放疗的患者出现颈椎放射性骨坏死并伴有四肢瘫痪：病例报告

Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer: a case report.

作者信息

van Wyk Frederik Carl, Sharma Manu-Priya, Tranter Robert

机构信息

Department of Otolaryngology and Head and Neck Surgery, Brighton and Sussex University Hospitals NHS Trust Eastern Road, Brighton UK.

出版信息

J Med Case Rep. 2009 Jun 10;3:7262. doi: 10.4076/1752-1947-3-7262.

DOI:10.4076/1752-1947-3-7262
PMID:19830155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2726539/
Abstract

INTRODUCTION

Osteoradionecrosis of the mandible and temporal bones has been extensively reported in literature, but cases of avascular necrosis of the cervical spine following radiotherapy to the larynx appear to be extremely rare. A review of the English language literature has shown only one other case where radiotherapy treatment of a laryngeal carcinoma has resulted in osteoradionecrosis of the cervical spine.

CASE PRESENTATION

We present the case of a 65 year old male patient who suffered from osteoradionecrosis of the cervical spine 20 years after radiotherapy treatment for a T1aN0M0 laryngeal carcinoma resulting in quadriplegia.

CONCLUSIONS

Radiotherapy carries a long-term risk of complications, including osteoradionecrosis which may present 20 years later with significant implications.

摘要

引言

下颌骨和颞骨的放射性骨坏死在文献中已有广泛报道，但喉癌放疗后颈椎出现缺血性坏死的病例似乎极为罕见。对英文文献的回顾显示，仅有另一例喉癌放疗导致颈椎放射性骨坏死的病例。

病例报告

我们报告一例65岁男性患者，其在T1aN0M0喉癌放疗20年后发生颈椎放射性骨坏死，导致四肢瘫痪。

结论

放疗存在长期并发症风险，包括放射性骨坏死，可能在20年后出现，具有重大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ef/2726539/8723b08cdf57/1752-1947-0003-0000007262-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ef/2726539/a9f97ac06046/1752-1947-0003-0000007262-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ef/2726539/8723b08cdf57/1752-1947-0003-0000007262-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ef/2726539/a9f97ac06046/1752-1947-0003-0000007262-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ef/2726539/8723b08cdf57/1752-1947-0003-0000007262-2.jpg

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