Bate A S, Sidebottom D, Cooper R G, Loftus M, Chattopadhyay C, Grennan D M
Rheumatic Diseases Centre, Hope Hospital, Salford, Manchester, U.K.
Dis Markers. 1990 Nov-Dec;8(6):317-21.
Restriction fragment length polymorphisms (RFLPs) of alpha-1-antitrypsin were studied in 99 subjects with rheumatoid arthritis alone, 21 subjects with rheumatoid arthritis and pulmonary fibrosis, 26 subjects with rheumatoid arthritis and bronchiectasis, and 86 controls. No associations with either rheumatoid arthritis itself or with the associated pulmonary disorders were noted in this U.K. Caucasoid population.
在99名单纯类风湿性关节炎患者、21名患类风湿性关节炎并伴有肺纤维化的患者、26名患类风湿性关节炎并伴有支气管扩张的患者以及86名对照者中,研究了α-1-抗胰蛋白酶的限制性片段长度多态性(RFLPs)。在这个英国白种人群体中,未发现与类风湿性关节炎本身或相关肺部疾病有任何关联。