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西班牙的腹型肥胖与心血管疾病、糖尿病和高脂血症的关系。

Relationship of abdominal obesity with cardiovascular disease, diabetes and hyperlipidaemia in Spain.

机构信息

Department of Medicine, Endocrine Division, Complejo Hospitalario Universitario, Santiago de Compostela University, Centro de Investigación Biomédica en Red, Fisiopatología de Obesidad & Nutrición (CIBERobn), Santiago de Compostela, Spain.

出版信息

Clin Endocrinol (Oxf). 2010 Jul;73(1):35-40. doi: 10.1111/j.1365-2265.2009.03727.x. Epub 2009 Oct 15.

Abstract

OBJECTIVES

To evaluate the relevance of obesity and abdominal obesity in the prevalence of cardiovascular disease (CVD), diabetes mellitus, hyperlipidaemia and hypertension in primary care patients and to ascertain whether waist circumference (WC) measurement should be included in routine clinical practice in addition to body mass index (BMI).

METHODS

As part of the IDEA study, primary care physicians from Spain recruited patients aged 18-80 years. WC and BMI and the presence of CVD, diabetes mellitus, hyperlipidaemia and hypertension were recorded. Finally, 17 980 were analysed. An age-related increase in adiposity was observed. Overall 33% were obese by BMI, and 51% of subjects presented abdominal obesity by the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) (WC > 102 cm for men and > 88 cm for women). Although there was a correlation between BMI and WC, they presented different distribution patterns. Women, but not men, with a high level of education, professional activity and smoking were associated with a lower WC. Abdominal obesity was significantly associated with CVD. Some subjects with abdominal obesity but lean by BMI, showed an increased prevalence of CVD and diabetes. Furthermore, abdominal obesity was strongly associated with dyslipidaemia and hypertension.

CONCLUSIONS

Half of the primary care patients studied showed abdominal obesity as measured by WC, whereas one-third was obese by BMI. Abdominal obesity was strongly associated with CVD and diabetes, even in patients lean by BMI. WC should be included in the routine clinical practice in addition to BMI.

摘要

目的

评估肥胖和腹型肥胖与初级保健患者中心血管疾病(CVD)、糖尿病、高脂血症和高血压患病率的相关性,并确定腰围(WC)测量是否应除体重指数(BMI)以外纳入常规临床实践。

方法

作为 IDEA 研究的一部分,西班牙的初级保健医生招募了年龄在 18-80 岁之间的患者。记录 WC 和 BMI 以及 CVD、糖尿病、高脂血症和高血压的存在情况。最终分析了 17980 例患者。观察到肥胖与年龄相关的增加。总体而言,33%的患者 BMI 肥胖,51%的患者腹部肥胖,采用国家胆固醇教育计划成人治疗专家组 III(NCEP-ATPIII)标准(男性 WC>102cm,女性 WC>88cm)。尽管 BMI 和 WC 之间存在相关性,但它们呈现出不同的分布模式。具有高教育水平、职业活动和吸烟习惯的女性,但不是男性,其 WC 较低。腹型肥胖与 CVD 显著相关。一些 BMI 瘦但腹型肥胖的患者,CVD 和糖尿病的患病率增加。此外,腹型肥胖与血脂异常和高血压密切相关。

结论

研究中一半的初级保健患者的 WC 显示存在腹型肥胖,而三分之一的患者 BMI 肥胖。腹型肥胖与 CVD 和糖尿病密切相关,即使 BMI 瘦的患者也是如此。WC 应除 BMI 以外纳入常规临床实践。

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