Bunnell Stephen C
Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA.
Immunity. 2009 Oct 16;31(4):531-3. doi: 10.1016/j.immuni.2009.09.011.
In this issue of Immunity, Beal et al. (2009) and Jenkins et al. (2009) demonstrate that relatively weak stimuli support synapse formation and microtubule polarization, but fail to trigger efficient killing because of their inability to recruit lytic granules to the synaptic cleft.
在本期《免疫》杂志中,比尔等人(2009年)和詹金斯等人(2009年)证明,相对较弱的刺激可支持突触形成和微管极化,但由于无法将溶细胞颗粒募集到突触间隙,因而无法触发有效的杀伤作用。