雷公藤甲素通过诱导主要应激蛋白HSP70对实验性自身免疫性脑脊髓炎产生保护和治疗作用。 - Suppr

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超能文献

Protective and therapeutic effect of triptolide in EAE explained by induction of major stress protein HSP70.

作者信息

van Eden Willem

出版信息

J Neuroimmunol. 2009 Dec 10;217(1-2):10-1. doi: 10.1016/j.jneuroim.2009.09.008. Epub 2009 Oct 14.

DOI:10.1016/j.jneuroim.2009.09.008

PMID:19833397

Abstract

摘要

相似文献

Protective and therapeutic effect of triptolide in EAE explained by induction of major stress protein HSP70.雷公藤甲素通过诱导主要应激蛋白HSP70对实验性自身免疫性脑脊髓炎产生保护和治疗作用。

J Neuroimmunol. 2009 Dec 10;217(1-2):10-1. doi: 10.1016/j.jneuroim.2009.09.008. Epub 2009 Oct 14.

Oral administration of triptolide ameliorates the clinical signs of experimental autoimmune encephalomyelitis (EAE) by induction of HSP70 and stabilization of NF-kappaB/IkappaBalpha transcriptional complex.雷公藤甲素口服给药通过诱导热休克蛋白70（HSP70）和稳定核因子κB/核因子κB抑制蛋白α（NF-κB/IκBα）转录复合物来改善实验性自身免疫性脑脊髓炎（EAE）的临床症状。

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Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.雷公藤甲素调节T细胞炎症反应并改善实验性自身免疫性脑脊髓炎。

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The suppressive effect of triptolide on chronic colitis and TNF-alpha/TNFR2 signal pathway in interleukin-10 deficient mice.雷公藤甲素对白介素-10缺陷小鼠慢性结肠炎及TNF-α/TNFR2信号通路的抑制作用

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Gene therapy with mitochondrial heat shock protein 70 suppresses visual loss and optic atrophy in experimental autoimmune encephalomyelitis.基因治疗与线粒体热休克蛋白 70 抑制实验性自身免疫性脑脊髓炎的视力丧失和视神经萎缩。

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A case of mistaken identity: HSPs are no DAMPs but DAMPERs.一个身份识别错误的案例：HSPs 不是 DAMPs 而是 DAMPERs。

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