Heil T, Martens D, Eyrich K
Klinik f. Anaesthesiologie und operative Intensivmedizin, Universitätsklinikum Steglitz der FU, Berlin.
Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:1137-40.
In a prospective study 50 patients who reported regular ethanol consumption and who underwent neck dissection were evaluated by clinical examination and the Munich alcohol test (MALT). 31 patients were not classified as alcohol abusers and none of them developed withdrawal symptoms (WS) postoperatively. 19 patients were diagnosed as alcohol abusers; 9 of them (group 1) received symptomatic therapy with clomethiazol and haloperidol, 10 patients (group 2) received continuous ethanol infusions (2-4 g/h) postoperatively as prophylaxis for WS. 6 patients in group 1 developed WS; none of group 2 developed WS. Thus the period of intensive care therapy of group 2 was significantly shorter (3.0 versus 11.5 days). It was concluded that postoperative continuous ethanol infusions prevent the occurrence of WS and should be administered to severely alcoholic patients.
在一项前瞻性研究中,对50名报告有规律饮酒且接受颈部清扫术的患者进行了临床检查和慕尼黑酒精测试(MALT)评估。31名患者未被归类为酗酒者,他们中没有人在术后出现戒断症状(WS)。19名患者被诊断为酗酒者;其中9名(第1组)接受了氯美噻唑和氟哌啶醇的对症治疗,10名患者(第2组)术后接受持续乙醇输注(2 - 4 g/h)以预防WS。第1组中有6名患者出现WS;第2组中无人出现WS。因此,第2组的重症监护治疗时间明显更短(3.0天对11.5天)。得出的结论是,术后持续乙醇输注可预防WS的发生,应给予重度酗酒患者。