Perry Christine, Hall Carly
University Hospitals Bristol NHS Foundation Trust.
Nurs Times. 2009;105(36):20-3.
After 70 years of antibiotic therapy, the threat of untreatable infections is again a reality with resistance to antibiotics increasing in both Gram positive and Gram negative bacteria. Antibiotic-resistant bacteria cause both community and healthcare associated infections, presenting challenges in treatment and management. The development of new and novel antibiotics, particularly for Gram negative bacteria, is worryingly lacking. This article reviews the current situation and examines future strategies to tackle the continued threat of bacterial resistance.
经过70年的抗生素治疗，随着革兰氏阳性菌和革兰氏阴性菌对抗生素的耐药性不断增加，无法治疗的感染威胁再次成为现实。耐抗生素细菌会引发社区感染和医疗保健相关感染，给治疗和管理带来挑战。令人担忧的是，新型抗生素，尤其是针对革兰氏阴性菌的新型抗生素，研发十分匮乏。本文回顾了当前形势，并探讨应对细菌耐药性持续威胁的未来策略。
