Audu B M, Takai I U, Chama C M, Bukar M, Kyari O
Department of Obstetrics and Gynaecology, University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria.
J Obstet Gynaecol. 2009 May;29(4):322-5. doi: 10.1080/01443610902807345.
Hydatidiform mole (HM), is a known cause of early pregnancy wastage and has the risk of malignant potential. This is a retrospective study of 71 patients who were managed for hydatidiform mole at the University of Maiduguri Teaching Hospital, (UMTH) Maiduguri over a 10-year period, from January 1996 to December 2005, inclusive. The objective of the study was to determine the incidence, risk factors, clinical presentations and histological types of HM. Case records of 71 histologically confirmed HM were studied. Their sociodemographic characteristics, clinical presentations and histology reports were obtained and analysed. The institutional incidence of molar pregnancy was 3.8/1,000 deliveries. Histological findings showed partial mole in 51 (71.8%) cases and complete mole in 20 (28.2%) cases. The peak age-specific incidence rate was 17.5 years. The leading presenting clinical feature was abnormal vaginal bleeding seen in 100%. No case of invasive mole was found. Maternal complications included severe haemorrhage requiring blood transfusion (30.0%) and infections (15.5%). There was no maternal death. In conclusion, the incidence of partial hydatidiform mole was found to be higher than that of complete variety in our environment and the identified risk factors were young age, low parity and previous history of HM.
葡萄胎（HM）是早期妊娠流产的已知原因，且有恶变风险。这是一项对1996年1月至2005年12月（含）期间在迈杜古里大学教学医院（UMTH）迈杜古里接受葡萄胎治疗的71例患者进行的回顾性研究。该研究的目的是确定葡萄胎的发病率、危险因素、临床表现和组织学类型。对71例经组织学确诊的葡萄胎病例记录进行了研究。获取并分析了他们的社会人口学特征、临床表现和组织学报告。葡萄胎妊娠的机构发病率为3.8/1000例分娩。组织学检查结果显示，51例（71.8%）为部分性葡萄胎，20例（28.2%）为完全性葡萄胎。特定年龄发病率的高峰年龄为17.5岁。最主要的临床表现是100%的患者出现异常阴道出血。未发现侵蚀性葡萄胎病例。孕产妇并发症包括需要输血的严重出血（30.0%）和感染（15.5%）。无孕产妇死亡。总之，在我们的环境中，发现部分性葡萄胎的发病率高于完全性葡萄胎，且确定的危险因素为年轻、低生育次数和既往葡萄胎病史。
