Egwuatu V E, Ozumba B C
Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Enugu.
Int J Gynaecol Obstet. 1989 Jul;29(3):219-25. doi: 10.1016/0020-7292(89)90258-0.
Forty-one molar pregnancies seen at the University Teaching Hospital Enugu, Nigeria during the 10-year period 1976-1985 are analyzed. The incidence of hydatidiform mole was 0.82 per 1000 pregnancies. The incidence of molar pregnancy was lowest among teenage women and increased markedly with advancing age over 35 years. Hyperemesis gravidarum, a relatively uncommon finding in Nigerian women during normal pregnancy was a prominent feature of molar pregnancy in the women. The incidence of postmolar gestational trophoblastic disease was 17%; choriocarcinoma occurred in 7% of the subjects. Molar pregnancy and postmolar malignant trophoblastic disease occurred much less frequently among the Igbo women of Enugu than the Yorubas of western Nigeria. Earlier and better recognition and treatment of hydatidiform mole will probably result in a decrease in the high rate of complications found during this study.
对1976年至1985年这10年间在尼日利亚埃努古大学教学医院所见的41例葡萄胎妊娠进行了分析。葡萄胎的发病率为每1000例妊娠0.82例。葡萄胎妊娠的发病率在青少年女性中最低，并随着年龄超过35岁而显著增加。妊娠剧吐在尼日利亚正常妊娠女性中相对少见，但却是这些女性葡萄胎妊娠的一个突出特征。葡萄胎后妊娠滋养细胞疾病的发病率为17%；绒毛膜癌发生在7%的受试者中。埃努古的伊博族女性中葡萄胎妊娠和葡萄胎后恶性滋养细胞疾病的发生率远低于尼日利亚西部的约鲁巴族女性。对葡萄胎的更早且更好的识别和治疗可能会降低本研究中发现的高并发症发生率。
