Department of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Diabetes Res Clin Pract. 2009 Dec;86(3):233-8. doi: 10.1016/j.diabres.2009.09.014. Epub 2009 Oct 15.
To identify risk factors associated with the presence of diabetes.
A diabetes survey was conducted in 2801 citizens aged 35-79 years living in 10 communities in Beijing, China. Participants were recruited by residents committees. 75g oral glucose tolerance test was performed to define diabetes according to the WHO 1999 criteria. Logistic regression analysis was used to estimate odds ratios (OR) for diabetes.
The prevalence of diabetes and impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) was 24.2% and 20.4% in men, respectively and 19.4% and 19.0% in women, respectively. The multivariate adjusted OR (95% CI) corresponding to a one standard deviation increase in age (year) was 1.52 (1.25,1.86), waist circumference (cm) 1.35 (1.12,1.63), serum triglycerides (mmol/L) 1.29 (1.09,1.54) and high density lipoprotein cholesterol (mmol/L) 0.74 (0.61,0.91) in men and 2.03 (1.77,2.33), 1.21 (1.06,1.38), 1.34 (1.21,1.49), 0.74 (0.66,0.84) in women, respectively. For diabetes family history they were 2.46 (1.66,3.65) in men and 2.39 (1.84,3.10) in women, and for hypertension 1.14 (0.77,1.68) in men and 1.54 (1.18,2.01) in women. There were no significant associations between the presence of diabetes and occupation, education level, household income, leisure time physical activities, current smoking and drinking status.
Age, diabetes family history, obesity, dyslipidemia and hypertension were all associated with the presence of diabetes in this study population.
确定与糖尿病发生相关的危险因素。
对居住在中国北京市 10 个社区的 2801 名 35-79 岁居民进行了糖尿病调查。采用居委会招募的方式选取参与者。根据世界卫生组织 1999 年标准，进行 75g 口服葡萄糖耐量试验以确定糖尿病。采用 logistic 回归分析估计糖尿病的比值比（OR）。
男性糖尿病及空腹血糖受损（IFG）和/或糖耐量受损（IGT）的患病率分别为 24.2%和 20.4%，女性分别为 19.4%和 19.0%。年龄（岁）每增加一个标准差，相应的多变量调整 OR（95%CI）为 1.52（1.25，1.86），腰围（cm）为 1.35（1.12，1.63），血清甘油三酯（mmol/L）为 1.29（1.09，1.54），高密度脂蛋白胆固醇（mmol/L）为 0.74（0.61，0.91）；女性相应的 OR 为 2.03（1.77，2.33）、1.21（1.06，1.38）、1.34（1.21，1.49）、0.74（0.66，0.84）。糖尿病家族史的 OR 为男性 2.46（1.66，3.65），女性 2.39（1.84，3.10）；高血压的 OR 为男性 1.14（0.77，1.68），女性 1.54（1.18，2.01）。糖尿病的发生与职业、教育水平、家庭收入、闲暇时间体力活动、当前吸烟和饮酒状况之间无显著关联。
在本研究人群中，年龄、糖尿病家族史、肥胖、血脂异常和高血压均与糖尿病的发生有关。
