Guyon G, Ladet S, Maestracci M, Jeziorski E, Foulongne V, Rodière M
Service des Urgences Pédiatriques, Hôpital Lapeyronie, CHU montpellier.
Arch Pediatr. 2009 Oct;16 Suppl 2:S85-8. doi: 10.1016/S0929-693X(09)75307-2.
West Nile Virus infection is an arbovirosis accidentally transmitted to humans from an aviary reservoir via an infected mosquito. Though a French surveillance network set up in 2001 reports low circulation in France, the virus is endemic in other territories. Approximately 80% of infected children remain asymptomatic, fever is seen in 20%, and very few develop a severe neurological disease in the patient's blood or spinal fluid. Treatment remains essentially symptomatic though new specific antiviral treatments and human immunization are currently being developed.
西尼罗河病毒感染是一种虫媒病毒病,通过受感染的蚊子意外地从鸟类宿主传播给人类。尽管2001年建立的法国监测网络报告该病毒在法国的传播率较低,但该病毒在其他地区呈地方性流行。大约80%的受感染儿童没有症状,20%出现发热,只有极少数患者会在血液或脑脊液中发展为严重的神经疾病。尽管目前正在研发新的特异性抗病毒治疗方法和人类疫苗,但治疗仍主要是对症治疗。