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微创心胸外科手术的八年经验。

Eight-year experience with minimally invasive cardiothoracic surgery.

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons, Columbia University Medical Center, 77 Fort Washington Avenue, Milstein Hospital, Suite 7-435, New York, NY, 10032, USA.

出版信息

World J Surg. 2010 Apr;34(4):611-5. doi: 10.1007/s00268-009-0260-7.

Abstract

BACKGROUND

Over the past decade, minimally invasive cardiac surgery (MICS) has emerged as an accepted approach for the management of cardiac disease that requires a surgical solution. We report the results of an 8-year, single-institution experience with MICS.

METHODS

Between January 1, 2000 and December 31, 2007, a total of 910 patients underwent MICS. Major cases included aortic valve procedures (71, 7.8%), coronary artery bypass grafting (96, 10.5%), atrioseptal defect repair (103, 11.3%), and mitral valve procedures (507, 55.7%). Major outcomes of interest included the complication and mortality rates.

RESULTS

The mean age of the patients was 57 +/- 15 years; the mean ejection fraction was 55% +/- 11%; and the mean body mass index was 26.1 +/- 4.9. Overall, 782 cases (85.9%) were performed through a mini-thoracotomy. Most of the cases were accomplished through central cannulation (765, 84.0%), and venous drainage was most commonly performed in a bicaval fashion (percutaneous superior vena cava and percutaneous inferior vena cava). The mean aortic cross-clamp and cardiopulmonary bypass (CPB) times were 58.1 +/- 44.9 and 101.9 +/- 66.8 min, respectively. Conversion to full sternotomy occurred in 10 patients, and the median length of stay in hospital was 6 days. The overall complication rate was 8.8%, and the 30-day mortality rate was 2.9%. In the multivariate logistic regression analysis, risk factors associated with in-hospital complications included age, CPB time, arterial cannulation location, conversion from off-CPB to on-CPB, hepatic insufficiency, and diabetes. In the multivariate hazards regression analysis, risk factors associated with mortality included postoperative stroke, renal failure, and sternal wound infection; CPB time; and previous surgery.

CONCLUSIONS

In our experience, minimally invasive approaches are effective and reproducible for a variety of cardiac operations, with acceptable operating time durations, morbidity, and mortality.

摘要

背景

在过去的十年中,微创心脏手术(MICS)已成为治疗需要手术治疗的心脏疾病的公认方法。我们报告了一个 8 年单中心 MICS 经验的结果。

方法

在 2000 年 1 月 1 日至 2007 年 12 月 31 日期间,共有 910 例患者接受了 MICS。主要病例包括主动脉瓣手术(71 例,7.8%)、冠状动脉旁路移植术(96 例,10.5%)、房间隔缺损修复术(103 例,11.3%)和二尖瓣手术(507 例,55.7%)。主要关注的结果包括并发症和死亡率。

结果

患者的平均年龄为 57 +/- 15 岁;平均射血分数为 55% +/- 11%;平均体重指数为 26.1 +/- 4.9。总体而言,782 例(85.9%)通过小开胸手术进行。大多数病例通过中央插管进行(765 例,84.0%),静脉引流最常采用双腔方式(经皮上腔静脉和经皮下腔静脉)。平均主动脉阻断和体外循环(CPB)时间分别为 58.1 +/- 44.9 和 101.9 +/- 66.8 分钟。10 例患者转为全胸骨切开术,中位住院时间为 6 天。总并发症发生率为 8.8%,30 天死亡率为 2.9%。在多变量逻辑回归分析中,与院内并发症相关的危险因素包括年龄、CPB 时间、动脉插管位置、从体外循环转为体内循环、肝功能不全和糖尿病。在多变量风险回归分析中,与死亡率相关的危险因素包括术后中风、肾衰竭和胸骨伤口感染;CPB 时间;和以前的手术。

结论

根据我们的经验,微创方法对于各种心脏手术是有效且可重复的,具有可接受的手术时间、发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71cb/2864437/78074afe42f8/268_2009_260_Fig1_HTML.jpg

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