凝血即时检验

Point-of-care testing in coagulation.

作者信息

Van Cott Elizabeth M

机构信息

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.

出版信息

Clin Lab Med. 2009 Sep;29(3):543-53. doi: 10.1016/j.cll.2009.06.016.

DOI:10.1016/j.cll.2009.06.016

PMID:19840686

Abstract

Point-of-care (POC) assays are available for a variety of coagulation tests. These assays are generally simple to perform and have a more rapid turnaround time than their central-laboratory counterparts. This article discusses the current status of coagulation POC methodologies, focusing on the potential clinical uses and the limitations of platelet function testing, prothrombin time/international normalized ratio, D-dimer, and activated clotting time (ACT). Additional studies are eagerly awaited regarding potential future uses of POC coagulation testing, including the role of platelet function testing and ACT heparin management systems.

摘要

即时检验（POC）可用于多种凝血检测。这些检测通常操作简单，与中心实验室检测相比周转时间更快。本文讨论了凝血POC方法的现状，重点关注血小板功能检测、凝血酶原时间/国际标准化比值、D - 二聚体和活化凝血时间（ACT）的潜在临床应用及局限性。关于POC凝血检测未来潜在用途的更多研究，包括血小板功能检测和ACT肝素管理系统的作用，正备受期待。