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一名儿童经局部及病灶内注射α2b干扰素并部分切除后复发性结膜乳头瘤消退

Resolution of recurrent conjunctival papilloma after topical and intralesional interferon alpha2b with partial excision in a child.

作者信息

Kothari Mihir, Mody Kruti, Chatterjee Debapriya

机构信息

Aditya Jyot Eye Hospital, Opp SIWS College Gate, Wadala, Mumbai, Maharashtra, India.

出版信息

J AAPOS. 2009 Oct;13(5):523-5. doi: 10.1016/j.jaapos.2009.08.014.

DOI:10.1016/j.jaapos.2009.08.014
PMID:19840738
Abstract

The human papilloma virus (HPV) is a double-stranded DNA virus that infects the epithelium of skin and mucosa. Simple treatment of conjunctival papilloma is associated with recurrences, and while most medical therapy has met with limited success, interferon alpha 2b (IFN alpha2b) may be effective. In this report, we describe a 7-year-old child with severe, recurrent conjunctival papilloma who had complete regression of the papilloma after topical and intralesional IFN alpha2b with partial excision of the lesion.

摘要

人乳头瘤病毒(HPV)是一种双链DNA病毒,可感染皮肤和黏膜上皮。结膜乳头瘤的单纯治疗易复发,虽然大多数药物治疗效果有限,但α2b干扰素(IFNα2b)可能有效。在本报告中,我们描述了一名7岁患有严重复发性结膜乳头瘤的儿童,在局部和病灶内注射IFNα2b并部分切除病变后,乳头瘤完全消退。

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Resolution of recurrent conjunctival papilloma after topical and intralesional interferon alpha2b with partial excision in a child.一名儿童经局部及病灶内注射α2b干扰素并部分切除后复发性结膜乳头瘤消退
J AAPOS. 2009 Oct;13(5):523-5. doi: 10.1016/j.jaapos.2009.08.014.
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Conjunctival papilloma.结膜乳头状瘤。
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引用本文的文献

1
Treatment of conjunctival papilloma with topical interferon alpha-2b - case report.局部应用干扰素α-2b治疗结膜乳头状瘤——病例报告
Medicine (Baltimore). 2020 Feb;99(7):e19181. doi: 10.1097/MD.0000000000019181.
2
Update on Diagnosis and Management of Conjunctival Papilloma.结膜乳头状瘤的诊断与管理最新进展
Eye Vis (Lond). 2019 Jun 18;6:18. doi: 10.1186/s40662-019-0142-5. eCollection 2019.
3
Conjunctival squamous papilloma refractory to interferon α-2b in a patient on systemic immunosuppression (tacrolimus).一名接受全身性免疫抑制(他克莫司)治疗的患者,其结膜鳞状乳头瘤对干扰素α-2b治疗无效。
Am J Ophthalmol Case Rep. 2017 Feb 3;6:1-3. doi: 10.1016/j.ajoc.2017.01.005. eCollection 2017 Jun.
4
Interferon alfa-2b in the management of recurrent conjunctival papillomatosis.干扰素α-2b在复发性结膜乳头瘤病治疗中的应用
Indian J Ophthalmol. 2016 Oct;64(10):778-780. doi: 10.4103/0301-4738.195013.
5
Interferons as therapeutic agents for infectious diseases.干扰素作为治疗传染病的药物。
Infect Dis Clin North Am. 2011 Dec;25(4):819-34. doi: 10.1016/j.idc.2011.07.008.