Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Łódź, Łódź, Poland.
Nat Prod Res. 2009;23(16):1507-21. doi: 10.1080/14786410802636177.
The antioxidant potential of 70% methanolic extracts from the inflorescences, leaves and fruits of Sorbus aucuparia, S. aria and S. intermedia was evaluated using three in vitro test systems (DPPH: 2,2-diphenyl-1-picryl hydrazyl; TEAC: trolox equivalent antioxidant capacity and FRAP: ferric reducing/antioxidant power). High activities found were expressed as micromoles trolox equivalents per gram dry weight and were in the range of 86.9-956.2 for the DPPH test, 65.3-577.2 for the TEAC assay and 221.1-1915.2 for the FRAP method. Significant linear correlations (R(2) in the range of 0.75-0.98) between these values and the contents of total phenolics, total flavonoids, total proanthocyanidins and chlorogenic acid isomers showed that the listed phenolic compounds are determinants of the antioxidant capacity tested. As the superior activity and the highest phenolic levels (11.83% of total phenolics calculated as gallic acid equivalents, 4.35% of chlorogenic acid isomers, 5.01% of proanthocyanidins and 1.28% of flavonoid aglycones) were found for S. aucuparia inflorescence, this plant material has the greatest potential as a source for natural health products.
采用三种体外测试系统(DPPH:2,2-二苯基-1-苦基肼基;TEAC:trolox 当量抗氧化能力和 FRAP:铁还原/抗氧化能力)评估了挪威槭(Sorbus aucuparia)、花楸(S. aria)和杂种花楸(S. intermedia)的花序、叶子和果实的 70%甲醇提取物的抗氧化潜力。发现的高活性以每克干重的 trolox 当量微摩尔表示,范围为 DPPH 测试 86.9-956.2,TEAC 测定 65.3-577.2,FRAP 方法 221.1-1915.2。这些值与总酚、总类黄酮、总原花青素和绿原酸异构体含量之间存在显著的线性相关性(R(2)范围为 0.75-0.98),表明列出的酚类化合物是测试抗氧化能力的决定因素。由于挪威槭花序具有优越的活性和最高的酚类水平(总酚的 11.83%计算为没食子酸当量,绿原酸异构体的 4.35%,原花青素的 5.01%和类黄酮苷元的 1.28%),因此这种植物材料具有作为天然保健品来源的最大潜力。