Lackritz E M, Lobel H O, Howell B J, Bloland P, Campbell C C
Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Ga 30333.
JAMA. 1991 Jan 16;265(3):383-5.
Data from the US National Malaria Surveillance System were analyzed to assess characteristics of travelers who acquired Plasmodium falciparum infections in Africa and evaluate the impact of chloroquine resistance on the incidence of imported malaria. Although the number of cases acquired in East Africa has stabilized, the number of imported P falciparum infections acquired in West Africa increased threefold from 1985 to 1988, and the proportion of travelers who reported failure of chloroquine prophylaxis increased from 10% to 48%. Fifty-eight percent of patients who acquired malaria in West Africa had not used chemoprophylaxis. To curb the rising incidence of P falciparum infections in American travelers, the Centers for Disease Control revised malaria prophylaxis recommendations to include the use of mefloquine in areas of chloroquine resistance. Use of malaria protection measures by travelers to West Africa must also be improved.
对美国国家疟疾监测系统的数据进行了分析，以评估在非洲感染恶性疟原虫的旅行者的特征，并评估氯喹耐药性对输入性疟疾发病率的影响。虽然在东非感染的病例数已趋于稳定，但从1985年到1988年，在西非感染的输入性恶性疟原虫病例数增加了两倍，报告氯喹预防治疗失败的旅行者比例从10%上升到48%。在西非感染疟疾的患者中有58%未使用化学预防措施。为遏制美国旅行者中恶性疟原虫感染发病率的上升，疾病控制中心修订了疟疾预防建议，将甲氟喹的使用纳入氯喹耐药地区。前往西非的旅行者的疟疾防护措施的使用也必须加以改进。
