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没有表观遗传学就没有遗传学?没有系统生物学就没有生物学?

No genetics without epigenetics? No biology without systems biology?

作者信息

Van de Vijver Gertrudis

机构信息

Centre for Critical Philosophy, Department of Philosophy and Moral Science, Faculty of Literature and Philosophy, Ghent University, Ghent, Belgium.

出版信息

Ann N Y Acad Sci. 2009 Oct;1178:305-17. doi: 10.1111/j.1749-6632.2009.05010.x.

DOI:10.1111/j.1749-6632.2009.05010.x
PMID:19845646
Abstract

In this article, we propose to reflect on the meaning of complexity in relation to current biology, and in particular, in relation to current systems biological developments by considering them as confronting biology with the idea of a complex part-whole determination of living systems, that is contextual as well as stratified. We attempt to trace as clearly as possible the abstract core of the idea of parts and wholes that is at stake in this contextual determination. In doing so, we have found inspiration in Kant's view on living systems. We argue that Kant's transcendental viewpoint can be relevantly actualized and extrapolated as a relational account of living systems, and will explore its ramifications starting from a multilevel view of living systems.

摘要

在本文中,我们提议思考复杂性相对于当前生物学的意义,尤其是相对于当前系统生物学发展的意义,通过将它们视为使生物学面对关于生命系统的复杂部分 - 整体决定的观念,这种决定既是情境性的也是分层的。我们试图尽可能清晰地追溯在这种情境决定中所涉及的部分与整体观念的抽象核心。在此过程中,我们从康德关于生命系统的观点中获得了灵感。我们认为,康德的先验观点可以作为一种关于生命系统的关系性解释而得到相关的实现和拓展,并将从生命系统的多层次视角出发探索其影响。

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