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静脉溃疡:标准外科手术后影响复发的因素

Venous ulceration: factors influencing recurrence after standard surgical procedures.

作者信息

Nash T P

机构信息

University of New South Wales Department of Surgery, St Vincent's Hospital, Darlinghurst, NSW.

出版信息

Med J Aust. 1991 Jan 7;154(1):48-50. doi: 10.5694/j.1326-5377.1991.tb112851.x.

DOI:10.5694/j.1326-5377.1991.tb112851.x
PMID:1984586
Abstract

Ninety patients with chronic venous ulceration were investigated to determine the extent of the incompetence of the venous valves. They were then treated by established surgical methods to control reflux. All wore fitted compression stockings and were regularly followed up. Forty-two patients had valvular incompetence confined to the perforating and superficial veins. All their ulcers healed and only one developed a minor recurrence during the three year follow-up. Nineteen patients had additional but limited incompetence of the deep veins; all their ulcers healed, but three developed a recurrence. Twenty-nine patients had extensive deep vein valvular incompetence including incompetence of the popliteal valve; in 12 of these patients either the ulcer failed to heal or the patient developed a recurrent ulcer within 18 months. Thirty-two other patients developed further venous reflux from the opening of new channels, including the perforating veins of the foot, and required sclerosants or local ligation. It was concluded that established surgical techniques, thoroughly performed, were very effective for the treatment of chronic venous ulceration provided the popliteal valves were competent. When the popliteal valves were incompetent the recurrence rate was unacceptably high and additional methods, including vein valve transplants, excision of the ulcer with skin grafting and lumbar sympathectomy, were considered. Nine of 11 patients who received a vein valve transplant had falls in their ambulant venous pressures, improvement in the nutrition of their skin and healing of their recurrent ulcers.

摘要

对90例慢性静脉溃疡患者进行了调查,以确定静脉瓣膜功能不全的程度。然后采用既定的手术方法治疗以控制反流。所有患者均穿着合适的压力袜并定期接受随访。42例患者的瓣膜功能不全仅限于穿通静脉和浅静脉。在三年的随访期间,他们所有的溃疡均愈合,只有1例出现轻微复发。19例患者还存在深静脉功能不全,但程度有限;他们所有的溃疡均愈合,但有3例复发。29例患者存在广泛的深静脉瓣膜功能不全,包括腘静脉瓣膜功能不全;在这些患者中,有12例患者的溃疡未能愈合,或者在18个月内出现复发性溃疡。另外32例患者因新通道开放,包括足部穿通静脉,出现了进一步的静脉反流,需要使用硬化剂或局部结扎治疗。得出的结论是,只要腘静脉瓣膜功能正常,彻底实施既定的手术技术对慢性静脉溃疡的治疗非常有效。当腘静脉瓣膜功能不全时,复发率高得令人无法接受,因此考虑采用包括静脉瓣膜移植、溃疡切除植皮和腰交感神经切除术在内的其他方法。接受静脉瓣膜移植的11例患者中有9例其行走时静脉压力下降,皮肤营养状况改善,复发性溃疡愈合。

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