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冠状动脉搭桥手术后与慢性特发性骨髓纤维化相关的坏疽性脓皮病。

Pyoderma gangrenosum associated with chronic idiopathic myelofibrosis after coronary artery bypass graft surgery.

作者信息

Sebastian Vinod A, Carroll Bryan T, Jessen Michael E

机构信息

Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.

出版信息

Interact Cardiovasc Thorac Surg. 2010 Jan;10(1):135-7. doi: 10.1510/icvts.2009.213512. Epub 2009 Oct 21.

Abstract

Pyoderma gangrenosum (PG) is an ulceronecrotizing dermatosis that can occur after minor trauma or surgery and is rare after cardiac surgery. We report a case of PG after coronary artery bypass grafting (CABG) in a patient with chronic idiopathic myelofibrosis (CIMF). Diagnosis was made with punch skin biopsy and he was treated with systemic steroids. His lesions showed remarkable improvement with this therapy. Cardiothoracic surgeons need to consider this diagnosis in all rapidly expanding postoperative lesions, especially those that do not improve with debridement or antibiotics or conservative wound care.

摘要

坏疽性脓皮病(PG)是一种溃疡坏死性皮肤病,可在轻微创伤或手术后发生,在心脏手术后较为罕见。我们报告一例慢性特发性骨髓纤维化(CIMF)患者冠状动脉旁路移植术(CABG)后发生PG的病例。通过皮肤穿刺活检做出诊断,并对其进行全身类固醇治疗。经此治疗,他的皮损有显著改善。心胸外科医生需要在所有术后迅速扩大的皮损中考虑这一诊断,尤其是那些经清创、抗生素治疗或保守伤口护理后无改善的皮损。

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