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[局部负压与皮肤移植治疗坏疽性脓皮病]

[Topical negative pressure and skin transplantation for the treatment of pyoderma gangrenosum].

作者信息

Gámiz Rocío Caballero, Nielsen Ana Marie

机构信息

Plastikkirurgisk Afdeling, Odense Universitetshospital, Denmark.

出版信息

Ugeskr Laeger. 2011 Aug 29;173(35):2132-3.

PMID:21884666
Abstract

Pyoderma gangrenosum (PG) is a rare idiopathic, autoimmune and inflammatory disease characterized by the development of ulcerative skin lesions. A 58 year-old woman, diagnosed with biopsy-verified PG was admitted to the Wound Center at Odense University Hospital, with rapid progression of painful, necrotic PG lesions on both crura. The lesions were treated, in collaboration with the dermatologists, with systemic steroids, topical negative pressure treatments and surgical revision in addition to partial skin graft with good results. Following the treatment the patient has been pain free and without recurrence for 11 months.

摘要

坏疽性脓皮病(PG)是一种罕见的特发性、自身免疫性炎症性疾病,其特征为溃疡性皮肤病变的形成。一名58岁女性,经活检确诊为PG,因双侧小腿疼痛性、坏死性PG病变迅速进展而入住欧登塞大学医院伤口中心。除部分皮肤移植外,与皮肤科医生合作,采用全身用类固醇、局部负压治疗和手术清创对病变进行了治疗,效果良好。治疗后,患者已11个月无疼痛且未复发。

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引用本文的文献

1
Surgical Treatment of Pyoderma Gangrenosum with Negative Pressure Wound Therapy and Skin Grafting, Including Xenografts: Personal Experience and Comprehensive Review on 161 Cases.采用负压伤口治疗和植皮(包括异种移植物)治疗坏疽性脓皮病的手术治疗:161 例的个人经验和综合回顾。
Adv Wound Care (New Rochelle). 2020 Jul;9(7):405-425. doi: 10.1089/wound.2020.1160. Epub 2020 Apr 28.
2
[Surgical management of Pyoderma gangrenosum].坏疽性脓皮病的外科治疗
Hautarzt. 2012 Jul;63(7):577-83. doi: 10.1007/s00105-011-2269-8.