Gámiz Rocío Caballero, Nielsen Ana Marie
Plastikkirurgisk Afdeling, Odense Universitetshospital, Denmark.
Ugeskr Laeger. 2011 Aug 29;173(35):2132-3.
Pyoderma gangrenosum (PG) is a rare idiopathic, autoimmune and inflammatory disease characterized by the development of ulcerative skin lesions. A 58 year-old woman, diagnosed with biopsy-verified PG was admitted to the Wound Center at Odense University Hospital, with rapid progression of painful, necrotic PG lesions on both crura. The lesions were treated, in collaboration with the dermatologists, with systemic steroids, topical negative pressure treatments and surgical revision in addition to partial skin graft with good results. Following the treatment the patient has been pain free and without recurrence for 11 months.
坏疽性脓皮病(PG)是一种罕见的特发性、自身免疫性炎症性疾病,其特征为溃疡性皮肤病变的形成。一名58岁女性,经活检确诊为PG,因双侧小腿疼痛性、坏死性PG病变迅速进展而入住欧登塞大学医院伤口中心。除部分皮肤移植外,与皮肤科医生合作,采用全身用类固醇、局部负压治疗和手术清创对病变进行了治疗,效果良好。治疗后,患者已11个月无疼痛且未复发。