Yunus M B, Ahles T A, Aldag J C, Masi A T
Department of Medicine, University of Illinois College of Medicine, Peoria 61656.
Arthritis Rheum. 1991 Jan;34(1):15-21. doi: 10.1002/art.1780340104.
Clinical features and psychological status determined by the Minnesota Multiphasic Personality Inventory (MMPI) in 103 patients with primary fibromyalgia syndrome (PFS) were analyzed by univariate and multivariate techniques to determine if clinical features were related to psychological status or were intrinsic to PFS per se. The central features of PFS, e.g., number of pain sites, number of tender points, fatigue, and poor sleep, were independent of psychological status. However, discriminant analysis identified 4 variables--patient-reported depression, anxiety, stress, and pain severity--which together predicted 3 MMPI subgroups with an accuracy of 55% (P less than 0.001); the only musculoskeletal feature--pain severity--alone provided an accuracy of only 34% (P greater than 0.05). These data suggest a new concept, that the central features of fibromyalgia are independent of the psychological status and are more likely related to the PFS itself. However, pain severity may be influenced by psychological factors.
采用单变量和多变量技术分析了103例原发性纤维肌痛综合征（PFS）患者的临床特征以及由明尼苏达多相人格调查表（MMPI）所确定的心理状态，以确定临床特征是与心理状态相关还是PFS本身所固有的。PFS的核心特征，如疼痛部位数量、压痛点数量、疲劳和睡眠不佳，与心理状态无关。然而，判别分析确定了4个变量——患者报告的抑郁、焦虑、压力和疼痛严重程度——这些变量共同预测了3个MMPI亚组，准确率为55%（P<0.001）；唯一的肌肉骨骼特征——疼痛严重程度——单独预测的准确率仅为34%（P>0.05）。这些数据提示了一个新的概念，即纤维肌痛的核心特征与心理状态无关，更可能与PFS本身相关。然而，疼痛严重程度可能受心理因素影响。
