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纤维肌痛、抑郁和/或焦虑患者与性别差异。

Patients With Fibromyalgia, Depression, and/or Anxiety and Sex Differences.

机构信息

School of Medicine, Universidad Cooperativa de Colombia, Medellín, Colombia.

Neurological Institute of Colombia, Medellín, Colombia.

出版信息

Am J Mens Health. 2022 Jul-Aug;16(4):15579883221110351. doi: 10.1177/15579883221110351.

DOI:10.1177/15579883221110351
PMID:35818673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9280828/
Abstract

Fibromyalgia is a syndrome characterized by chronic widespread pain, with a multifactorial etiopathogenesis and high incidence of neuropsychiatric comorbidity. It has been inaccurately considered a pathological condition affecting only middle-aged women. The study aimed to explore the association of sociodemographic and clinical factors in patients with fibromyalgia with depression and/or anxiety. The present study is an analysis of a cross-sectional study of a secondary source. The prevalence ratio (PR) between the demographic and clinical variables of patients with fibromyalgia and concomitant depression and/or anxiety was calculated. Overall, 1,106 medical records were obtained with a confirmed diagnosis of fibromyalgia between 2010 and 2016; of these, 318 (28.75%) patients had an associated diagnosis of depression and/or anxiety. Approximately 28% women (295 of 1,052) and 42.6% men (23 of 54) suffered from depression and/or anxiety. In the adjusted explanatory model of depression and/or anxiety in patients with fibromyalgia, the relationship between sex (female PR = 0.5 [0.28-0.86]) and low socioeconomic strata (PR = 0.53 [0.33-0.70]) remained constant. In the study population, patients with fibromyalgia belonging to lower social strata were less likely to present with depression and anxiety. The male sex may pose as a risk factor for depression and/or anxiety in patients with fibromyalgia. Fibromyalgia has a huge impact on men's physical as well as mental health.

摘要

纤维肌痛是一种以慢性广泛性疼痛为特征的综合征,其发病机制具有多因素性,且发病率较高的神经精神合并症。它一直被不准确地认为是一种仅影响中年女性的病理状况。本研究旨在探讨纤维肌痛患者的社会人口统计学和临床因素与抑郁和/或焦虑的相关性。本研究是对二次来源的横断面研究进行的分析。计算了纤维肌痛患者的人口统计学和临床变量与并发抑郁和/或焦虑之间的患病率比(PR)。总体而言,在 2010 年至 2016 年间获得了 1106 份经证实患有纤维肌痛的病历;其中,318 名(28.75%)患者存在并发抑郁和/或焦虑的诊断。大约 28%的女性(1052 名中的 295 名)和 42.6%的男性(54 名中的 23 名)患有抑郁和/或焦虑。在纤维肌痛患者抑郁和/或焦虑的调整解释模型中,性别(女性 PR = 0.5 [0.28-0.86])和低社会经济阶层(PR = 0.53 [0.33-0.70])之间的关系保持不变。在研究人群中,社会地位较低的纤维肌痛患者出现抑郁和焦虑的可能性较小。男性可能是纤维肌痛患者抑郁和/或焦虑的危险因素。纤维肌痛对男性的身心健康都有巨大影响。

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Semin Arthritis Rheum. 2021 Feb;51(1):166-174. doi: 10.1016/j.semarthrit.2020.10.006. Epub 2020 Dec 29.
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Sex-Related Differences in Symptoms and Psychosocial Outcomes in Patients With Fibromyalgia: A Prospective Questionnaire Study.纤维肌痛患者症状及心理社会结局的性别差异:一项前瞻性问卷调查研究
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Gender differences on psychological factors in fibromyalgia: a systematic review on the male experience.纤维肌痛症心理因素的性别差异:男性体验的系统评价。
Clin Exp Rheumatol. 2021 May-Jun;39 Suppl 130(3):174-185. doi: 10.55563/clinexprheumatol/73g6np. Epub 2020 Dec 2.
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Fibromyalgia.纤维肌痛
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Fibromyalgia and its New Lessons for Neuropsychiatry.纤维肌痛及其给神经精神病学带来的新启示。
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