Shi P, Hu S, Zhu Y, Zheng J, Qiu Y, Cheang P Y S
Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, PR China.
J Med Eng Technol. 2009;33(8):628-33. doi: 10.3109/03091900903150980.
This study aims to investigate arterial stiffness in selected young adults by non-invasively determining the characteristics of the photoplethysmographic dicrotic notch. A total of 15 volunteers participated in this study, divided into four groups by age and gender. Contour analysis was applied to analyse the photoplethysmographic dicrotic notch, including time-related and height-related parameters. The height of reflected wave, mirrored by the notch relative amplitude (NRA), was found to be significantly larger in the older group compared to the younger group (p = 0.016). The timing of the reflected wave, measured by three parameters, i.e. notch index (NI), notch latency (NL) and peak-to-notch latency (PTNL), significantly increased in the female group compared to the male group (all p < 0.02). The results confirm that arterial stiffness occurs in young adults, and demonstrate that a difference of arterial stiffness exists between young male and female. This study indicates that examining the characteristic notch of the PPG pulse could help in identifying differences of vascular activities.
本研究旨在通过非侵入性地确定光电容积脉搏波重搏波切迹的特征，来调查特定年轻成年人的动脉僵硬度。共有15名志愿者参与了本研究，按年龄和性别分为四组。应用轮廓分析来分析光电容积脉搏波重搏波切迹，包括与时间相关和与高度相关的参数。发现由切迹相对振幅（NRA）反映的反射波高度，在老年组中显著高于年轻组（p = 0.016）。由三个参数测量的反射波时间，即切迹指数（NI）、切迹潜伏期（NL）和峰到切迹潜伏期（PTNL），在女性组中显著长于男性组（所有p < 0.02）。结果证实年轻成年人会出现动脉僵硬度，并且表明年轻男性和女性之间存在动脉僵硬度差异。本研究表明，检查PPG脉搏的特征切迹有助于识别血管活动的差异。
