Departament de Química Física, Universitat de Barcelona, Martí i Franquès 1, Barcelona, 08028, Spain.
Phys Chem Chem Phys. 2009 Nov 14;11(42):9615-25. doi: 10.1039/b910427e. Epub 2009 Aug 25.
This article reports several recent discoveries related to the controlled transport of paramagnetic colloidal particles above magnetic garnet films. The garnet films are thin uniaxial ferromagnetic films in which ferromagnetic domains can be organized into symmetric patterns consisting of stripes or bubbles and generate strong local magnetic field gradients. Application of an external homogeneous magnetic field on a larger scale compared to the spatial periodicity of the magnetic pattern in the film modulates the potential generated at its surface and induces the controlled motion of colloidal particles placed above the film. Several novel dynamical regimes are observed and reported, from localized trajectories to direct particle transport, depending on the geometry of the underlying magnetic pattern and on the parameters, which control the external driving field, such as frequency, strength and direction. Moreover, we show that this strategy allows separation and sorting of bi-disperse particle systems based on the particle size as well as the transport of chemical or biological cargoes attached to the colloidal carriers. Controlled transport of micro-sized cargoes (chemical or biological) by colloidal particle carriers in a microfluidic environment can bring significant contributions in several fields from targeted drug delivery to the realization of precise fluid-based micro-scale devices.
本文报道了几项与在石榴石薄膜上的顺磁胶体颗粒的可控输运相关的最新发现。石榴石薄膜是薄的单轴铁磁薄膜,其中铁磁畴可以组织成由条纹或气泡组成的对称图案,并产生强的局部磁场梯度。与薄膜中磁图案的空间周期性相比,施加在更大尺度上的外同强磁场调制了在其表面产生的势,并诱导了放置在薄膜上方的胶体颗粒的受控运动。观察到并报告了几种新颖的动力学状态,从局部轨迹到直接的粒子输运,这取决于底层磁图案的几何形状和控制外部驱动场的参数,如频率、强度和方向。此外,我们表明,这种策略允许基于颗粒尺寸对双分散颗粒系统进行分离和分类,以及对附着在胶体载体上的化学或生物货物的运输。在微流环境中通过胶体颗粒载体对微尺度货物(化学或生物)的可控输运可以在多个领域做出重要贡献,从靶向药物输送到精确的基于流体的微尺度器件的实现。