Ferreira Leonardo Mello, Emerich Paulo Sergio, Diniz Lucia Martins, Lage Luciene, Redighieri Isabella
Escola de Medicina da Santa Casa de Misericórdia de Vitória, ES, Brasil.
An Bras Dermatol. 2009 Jul-Aug;84(4):405-9. doi: 10.1590/s0365-05962009000400013.
Langerhans cell histiocytosis is defined as a clonal proliferation of Langerhans phenotypic-like cells. Letterer-Siwe disease is the most common and serious of these entities, affecting mainly infants up to two years of age. We present two cases of this rare disease, diagnosed after dermatological examination, highlighting its typical aspects.
朗格汉斯细胞组织细胞增多症被定义为朗格汉斯表型样细胞的克隆性增殖。勒-雪病是这些病症中最常见且最严重的，主要影响两岁以下的婴儿。我们呈现两例这种罕见疾病的病例，它们经皮肤科检查后确诊，突出了其典型特征。
