Tchicaya Emile S, Koudou Benjamin G, Keiser Jennifer, Adja Akré M, Cissé Gueladio, Tanner Marcel, Tano Yao, Utzinger Jürg
Centre Suisse de Recherches Scientifiques, Abidjan, Côte d'Ivoire.
J Am Mosq Control Assoc. 2009 Sep;25(3):382-5. doi: 10.2987/08-5809.1.
The effect of repeated applications of Bacillus thuringiensis var israeliensis (Bti) and B. sphaericus (Bs) on different entomologic parameters of malaria transmission was investigated in a village in central Côte d'Ivoire. The study area was monitored for potential mosquito breeding sites over a 7-month period. Microbial larvicides were applied once every 3 wk; first Bti (0.8 mg/liter), followed by Bs (10 mg/liter) 3-4 days later. Adult mosquitoes were collected inside and outside sentinel houses in 4 cross-sectional surveys using human landing catch. Repeated applications of Bti and Bs showed a decline in the biting rate of both Anopheles funestus and Anopheles gambiae. Moreover, the entomologic inoculation rate of An. funestus was significantly reduced (from 328 to 142, P = 0.005), whereas that of An. gambiae remained stable. In conclusion, microbial larvicides might play a role in an integrated approach for malaria control.
在科特迪瓦中部的一个村庄，研究了重复施用苏云金芽孢杆菌以色列变种（Bti）和球形芽孢杆菌（Bs）对疟疾传播的不同昆虫学参数的影响。在7个月的时间里，对研究区域内潜在的蚊虫滋生地进行了监测。微生物杀幼虫剂每3周施用一次；先施用Bti（0.8毫克/升），3至4天后再施用Bs（10毫克/升）。在4次横断面调查中，使用人饵诱捕法在哨房内外收集成蚊。重复施用Bti和Bs后，冈比亚按蚊和嗜人按蚊的叮咬率均有所下降。此外，嗜人按蚊的昆虫学接种率显著降低（从328降至142，P = 0.005），而冈比亚按蚊的昆虫学接种率保持稳定。总之，微生物杀幼虫剂可能在疟疾综合防治方法中发挥作用。
