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生精胶囊治疗少弱精子症患者的临床疗效

[Clinical efficacy of Shengjing capsule on patients with oligoasthenospermia].

作者信息

Song Fang-Wen, Zhong Wei-De

机构信息

Department of Urology, Dongguan Kanghua Hospital, Donguan, Guangdong 523080, China.

出版信息

Zhonghua Nan Ke Xue. 2009 Aug;15(8):762-4.

Abstract

OBJECTIVE

To investigate the clinical effect of the Chinese medicinal preparation Shengling Capsule on patients with oligoasthenospermia.

METHODS

A total of 270 male patients with infertility induced by oligoasthenospermia were equally divided into a treatment and a control group, the former medicated with Shengling Capsule at the dose of 1.6 g tid, and the latter given Vit E at 50 mg tid, both for a course of 12 weeks. Then we analyzed the changes in the patients'seminal parameters and the pregnancy of their wives.

RESULTS

After 12 weeks of medication, both the seminal parameters of the patients and pregnancy of their wives were remarkably improved, with extremely significant differences from pre-treatment and the control (P < 0.01).

CONCLUSION

Shengjing Capsule can improve sperm motility and vitality as well as sperm count. With few adverse effects, it can be used as a safe and effective therapeutic for male infertility induced by oligoasthenospermia.

摘要

目的

探讨中药制剂生精胶囊治疗少弱精子症患者的临床疗效。

方法

将270例少弱精子症所致男性不育患者随机分为治疗组和对照组,每组135例。治疗组给予生精胶囊,每次1.6 g,每日3次;对照组给予维生素E,每次50 mg,每日3次。两组均连续服用12周,观察患者精液参数变化及配偶妊娠情况。

结果

治疗12周后,治疗组患者精液参数及配偶妊娠率均显著改善,与治疗前及对照组比较,差异均有统计学意义(P < 0.01)。

结论

生精胶囊可提高精子活力、活率及精子密度,不良反应少,可作为治疗少弱精子症所致男性不育的安全、有效药物。

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