Honig Stephen
New York University School of Medicine, New York, New York, USA.
Bull NYU Hosp Jt Dis. 2009;67(3):281-4.
The need to initiate treatment for a postmenopausal woman with a low bone mass should be based on that individual's fracture risk over a fnite period of time. Fracture assessment tools, such as the recently introduced FRAX(TM) model, allows the clinician to estimate an individual's absolute fracture risk over the next decade of their life. Such estimates are particularly useful for younger postmenopausal females with bone density values in the osteopenic range. Fracture risk increases with age and is inversely related to bone mineral density values. A history of previous fracture after the age of 45 and within 10 years of assessment increases subsequent fracture risk.
对于骨量低的绝经后女性，启动治疗的必要性应基于该个体在有限时间段内的骨折风险。骨折评估工具，如最近推出的FRAX™模型，使临床医生能够估计个体在其未来十年生命中的绝对骨折风险。此类估计对于骨密度值处于骨质减少范围的年轻绝经后女性尤为有用。骨折风险随年龄增加而上升，且与骨矿物质密度值呈负相关。45岁之后且在评估的10年内有既往骨折史会增加后续骨折风险。
