高通量 9216 微孔细胞阵列用于高内涵筛选显微镜。

Next-generation 9216-microwell cell arrays for high-content screening microscopy.

机构信息

ViroQuant-CellNetworks RNAi Screening Facility, BioQuant, University of Heidelberg, Germany.

出版信息

Biotechniques. 2009 Oct;47(4):877-8. doi: 10.2144/000113251.

PMID:19852772

Abstract

Reverse transfection on cell arrays is a high-throughput method for the parallel transfection of mammalian cells for use in high-content screening light microscopy. Here, we present novel 9216-microwell cell arrays which combine the advantages of multiwell plates (physically separated samples) and cell microarrays (high sample density and long-term storage).

摘要

细胞微阵列的反向转染是一种高通量的方法，用于平行转染哺乳动物细胞，用于高内涵筛选的显微镜检测。在这里，我们提出了新颖的 9216 微孔细胞阵列，它结合了多孔板（物理分离的样品）和细胞微阵列（高样品密度和长期存储）的优点。