Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA; Department of Psychiatry, Rush University Medical Center, Armour Academic Center, 600 South Paulina Street, Suite 202 Chicago, IL 60612, USA; Laboratory of Electroencephalography and Video-EEG-Telemetry, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA; Section of Epilepsy and Rush Epilepsy Center, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA.
Neurol Clin. 2009 Nov;27(4):865-880. doi: 10.1016/j.ncl.2009.08.002.
Depressive disorders are the most frequent comorbidity of PWE. As discussed in this article, the depressive disorder is another expression of a neurologic disorder with psychiatric symptoms. The high comorbidity of both conditions can be explained by the existence of common pathogenic mechanisms whereby one condition facilitates the occurrence of the other. The negative impact of depressive disorders in the life of PWE is significant; hence, a prompt recognition should be followed by a treatment designed to yield complete symptom remission.
抑郁障碍是 PWE 最常见的合并症。正如本文所讨论的，抑郁障碍是具有精神症状的神经障碍的另一种表现。这两种疾病的高共病性可以用共同的发病机制来解释，即一种疾病促进另一种疾病的发生。抑郁障碍对 PWE 生活的负面影响是巨大的；因此，及时识别后应进行旨在实现完全症状缓解的治疗。
