Baguelin-Pinaud A, Moinier D, Fouldrin G, Le Roy F, Etienne I, Godin M, Thibaut F
Service Universitaire de Psychiatrie, CHU Charles-Nicolle, 76000 Rouen, France.
Encephale. 2009 Oct;35(5):429-35. doi: 10.1016/j.encep.2008.06.011. Epub 2008 Oct 31.
Until now there are few data in the literature describing psychiatric comorbidity in patients waiting for renal transplantation. We have conducted a cross sectional study estimating the prevalence of anxiety and depressive disorders in three groups of renal transplant patients, before transplantation, six months and one year after. The MINI was used to estimate the prevalence of anxiety and depressive disorders. Anxiety and depressive symptoms were assessed using the HAD. Patients' quality of life was also assessed using the SF-36. This study did not find any major impact of renal transplantation on the prevalence of structured psychiatric disorders. Indeed, the prevalence of depressive and anxiety disorders did not differ significantly between the three groups. The mean scores of anxiety did not differ significantly between the three groups in contrast to the mean scores of depression, which differed significantly between the group "before transplantation" and the group "one year after transplantation". We did not find any significant difference concerning the scores of patient's quality of life between the three groups, except for the item "health perceived by the patients themselves". Health perceived by the patients was greater in the group "after transplantation". The quality of life of dialysed or transplant patients was strongly correlated with anxiety and depressive symptoms scores, emphasizing the major interest of a multidisciplinary approach for these patients.
到目前为止，文献中几乎没有关于等待肾移植患者精神共病情况的数据。我们进行了一项横断面研究，估计三组肾移植患者在移植前、移植后六个月和一年时焦虑症和抑郁症的患病率。使用MINI来估计焦虑症和抑郁症的患病率。使用HAD评估焦虑和抑郁症状。还使用SF - 36评估患者的生活质量。本研究未发现肾移植对结构性精神障碍患病率有任何重大影响。事实上，三组之间抑郁和焦虑症的患病率没有显著差异。与抑郁症的平均得分相比，三组之间焦虑的平均得分没有显著差异，抑郁症的平均得分在“移植前”组和“移植后一年”组之间有显著差异。除了“患者自身感知的健康状况”这一项外，我们未发现三组患者生活质量得分有任何显著差异。“移植后”组患者对自身健康状况的感知更好。透析患者或移植患者的生活质量与焦虑和抑郁症状得分密切相关，强调了对这些患者采取多学科方法的重要意义。
