Caballero Gullón L, Cardo A L Gutiérrez, Tirado Hospital J L, Rodríguez J R Rodríguez, Albertino R Vázquez
Unidad de Gestión Diagnóstica de Medicina Nuclear, Hospital Universitario Virgen del Rocío, Sevilla, España.
Rev Esp Med Nucl. 2009 Nov-Dec;28(6):283-7. doi: 10.1016/j.remn.2009.09.002. Epub 2009 Oct 24.
The aim of this study is to determine the diagnostic reliability of the renogram with diuretic stimulus simultaneously at the administration of the dose, comparing two groups of 59 patients each one (F0 and F+10), to select patients for surgery.
This is an retrospective study about two groups of 59 patients to whom the diuretic renogram was carried out by stimulus (furosemide), by suspicion of ureteropelvic or vesicoureteral obstruction, using (99m)Tc-Mercaptoacetylglicine. In the first one, the study was conducted applying the diuretic stimulus 600 seconds after the administration of the dose of the radiotracer (F+10). In the second one it was carried out simultaneously to the administration (F0). For the interpretation there was used the visual analysis, the parameters of the curves and the percentage of elimination after modification by the severity and micturition. Statistical analysis of the information was made.
The F+10 renogram shows a sensitivity of 96,7%, specificity of 96,1%, positive predictive value of 90,6%, and a negative predictive value of 98,6%. The F0 renogram shows a sensitivity of 95,2%, specificity of 98,9%, positive predictive value of 95,2%, and a negative predictive value of 98,9%.
The performance of renogram by means of the administration of diuretic stimulus at the same time as the administration of the radiotracer is a useful and comfortable method in paediatric patients, not supposing a significant wastage in the parameters of efficiency of the test in the patients selection for surgery.
本研究旨在通过比较两组各59例患者（F0和F + 10），确定在给药时同时进行利尿刺激的肾图的诊断可靠性，以选择手术患者。
这是一项回顾性研究，对两组各59例因怀疑输尿管肾盂或膀胱输尿管梗阻而接受（99m）Tc - 巯基乙酰甘氨酸利尿肾图检查的患者进行研究。在第一组中，在给予放射性示踪剂剂量后600秒应用利尿刺激进行研究（F + 10）。在第二组中，在给药时同时进行（F0）。采用视觉分析、曲线参数以及根据严重程度和排尿情况修改后的消除百分比进行解读。对信息进行了统计分析。
F + 10肾图的敏感性为96.7%，特异性为96.1%，阳性预测值为90.6%，阴性预测值为98.6%。F0肾图的敏感性为95.2%，特异性为98.9%，阳性预测值为95.2%，阴性预测值为98.9%。
在给予放射性示踪剂的同时给予利尿刺激进行肾图检查，对于儿科患者是一种有用且便捷的方法，在选择手术患者时不会导致检查效率参数出现显著损耗。
