West Midlands Perinatal Institute, Birmingham B6 5RQ, UK.
Best Pract Res Clin Obstet Gynaecol. 2009 Dec;23(6):741-9. doi: 10.1016/j.bpobgyn.2009.09.001. Epub 2009 Oct 24.
The study of associations between intrauterine growth restriction (IUGR) and adverse outcome benefits from the use of a birthweight standard which is based on customised growth potential. Its application is able to retrospectively quantify the strength of the link with IUGR, whether fetal growth problems were identified antenatally or not. Furthermore, growth failure hitherto unrecognised by conventional standards, such as the average size but relatively small babies of mothers with high body mass index, identify IUGR as a cause of the increased perinatal mortality risk in obese pregnancies. Fetal growth restriction is found to be a frequent antecedent of perinatal morbidity and mortality, pointing to the need to improve its timely antenatal detection as a mainstay of management and prevention.
胎儿宫内生长受限(IUGR)与不良结局之间的关联研究受益于使用基于个体化生长潜能的出生体重标准。该标准的应用能够回顾性地量化与 IUGR 的关联强度,无论胎儿生长问题是否在产前被识别。此外,通过常规标准无法识别的生长失败,如母亲体重指数高的婴儿平均大小但相对较小,将 IUGR 确定为肥胖孕妇围产儿死亡风险增加的原因。胎儿生长受限被发现是围产发病率和死亡率的常见前兆,这表明需要提高其在产前的及时检测,作为管理和预防的主要手段。