HLA - DRB1*0901降低日本类风湿性关节炎患者的抗环瓜氨酸肽抗体水平。 - Suppr

HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.

作者信息

Okada Yukinori, Suzuki Akari, Yamada Ryo, Kochi Yuta, Shimane Kenichi, Myouzen Keiko, Kubo Michiaki, Nakamura Yusuke, Yamamoto Kazuhiko

出版信息

Ann Rheum Dis. 2010 Aug;69(8):1569-70. doi: 10.1136/ard.2009.118018. Epub 2009 Oct 22.

DOI:10.1136/ard.2009.118018

PMID:19854714

Abstract

摘要

相似文献

HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.HLA - DRB1*0901降低日本类风湿性关节炎患者的抗环瓜氨酸肽抗体水平。

Ann Rheum Dis. 2010 Aug;69(8):1569-70. doi: 10.1136/ard.2009.118018. Epub 2009 Oct 22.

Differential association of HLA-DRB1 alleles in Japanese patients with early rheumatoid arthritis in relationship to autoantibodies to cyclic citrullinated peptide.日本早期类风湿关节炎患者中HLA - DRB1等位基因与抗环瓜氨酸肽自身抗体的差异关联。

Clin Exp Rheumatol. 2007 Mar-Apr;25(2):219-24.

Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles.类风湿关节炎患者血清中对瓜氨酸化抗原的多种抗体反应性：与HLA - DRB1等位基因的关联

Ann Rheum Dis. 2009 May;68(5):736-43. doi: 10.1136/ard.2008.091355. Epub 2008 Jul 17.

HLA-DRB1 and anti-cyclic citrullinated peptide antibody production in rheumatoid arthritis.类风湿关节炎中HLA - DRB1与抗环瓜氨酸肽抗体的产生

Int Arch Allergy Immunol. 2005 Aug;137(4):315-8. doi: 10.1159/000086463. Epub 2005 Jun 20.

HLA-DRB1*0404 is strongly associated with high titers of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis.HLA - DRB1*0404与类风湿关节炎中高滴度的抗环瓜氨酸肽抗体密切相关。

Clin Exp Rheumatol. 2008 Jul-Aug;26(4):627-31.

Anti-glucose-6-phosphate isomerase, anti-cyclic citrullinated peptide antibodies and HLA-DRB1 genotypes in Japanese patients with early rheumatoid arthritis.日本早期类风湿关节炎患者的抗葡萄糖-6-磷酸异构酶、抗环瓜氨酸肽抗体及HLA-DRB1基因型

Clin Exp Rheumatol. 2008 Sep-Oct;26(5):918-21.

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles.仅在携带HLA - DRB1共享表位等位基因的类风湿关节炎患者中，吸烟才是抗环瓜氨酸肽抗体的一个风险因素。

Ann Rheum Dis. 2006 Mar;65(3):366-71. doi: 10.1136/ard.2005.041079. Epub 2005 Jul 13.

Associations of HLA-DRB1 alleles with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in northern east part of Turkey.在土耳其东北部，HLA-DRB1 等位基因与抗瓜氨酸化蛋白抗体阳性和抗瓜氨酸化蛋白抗体阴性类风湿关节炎的关联。

Int J Rheum Dis. 2012 Dec;15(6):538-45. doi: 10.1111/j.1756-185X.2011.01604.x. Epub 2011 Mar 4.

Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen.HLA - DR基因对类风湿关节炎特异性抗瓜氨酸化纤维蛋白原自身抗体产生的影响。

Arthritis Rheum. 2005 Nov;52(11):3424-32. doi: 10.1002/art.21391.

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis.人类白细胞抗原（HLA）II类基因与抗环瓜氨酸肽（CCP）自身抗体之间的关联会影响类风湿性关节炎的严重程度。

Arthritis Rheum. 2004 Jul;50(7):2113-21. doi: 10.1002/art.20316.

引用本文的文献

Revisiting the Link Between HLA-DRB1 Alleles and Autoantibodies in Rheumatoid Arthritis: Association of non-Shared Epitope Alleles *09 and *15 With High Levels of Anti-Citrullinated Peptide/Protein Antibodies.重新审视类风湿关节炎中HLA - DRB1等位基因与自身抗体之间的联系：非共享表位等位基因*09和*15与高水平抗瓜氨酸化肽/蛋白抗体的关联。

ACR Open Rheumatol. 2025 Jan;7(1):e11767. doi: 10.1002/acr2.11767. Epub 2024 Nov 22.

Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis: data from a randomised controlled trial.类风湿因子、抗瓜氨酸化蛋白抗体和共享表位与早期类风湿关节炎患者初始治疗临床反应的相关性：一项随机对照试验的数据。

Ann Rheum Dis. 2024 Nov 14;83(12):1657-1665. doi: 10.1136/ard-2024-226024.

The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study.在多样化亚洲人群中HLA区域与类风湿关节炎的关联谱：来自MyEIRA病例对照研究的证据

Arthritis Res Ther. 2021 Jan 30;23(1):46. doi: 10.1186/s13075-021-02431-z.

Genetic landscape of interactive effects of alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population.日本人群中等位基因相互作用对 ACPA(+)类风湿关节炎易感性和 ACPA 水平影响的遗传图谱。

J Med Genet. 2017 Dec;54(12):853-858. doi: 10.1136/jmedgenet-2017-104779. Epub 2017 Oct 12.

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis.非经典HLA基因HLA - DOA对类风湿关节炎风险的影响

Am J Hum Genet. 2016 Aug 4;99(2):366-74. doi: 10.1016/j.ajhg.2016.06.019.

Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis.类风湿关节炎遗传基础界定的最新进展

Annu Rev Genomics Hum Genet. 2016 Aug 31;17:273-301. doi: 10.1146/annurev-genom-090314-045919. Epub 2016 May 23.

Construction of a population-specific HLA imputation reference panel and its application to Graves' disease risk in Japanese.构建特定人群 HLA 单体型推断参考面板及其在日本 Graves 病风险中的应用。

Nat Genet. 2015 Jul;47(7):798-802. doi: 10.1038/ng.3310. Epub 2015 Jun 1.

Genetics of rheumatoid arthritis in Asia--present and future.亚洲类风湿关节炎的遗传学——现状与未来。

Nat Rev Rheumatol. 2015 Jun;11(6):375-9. doi: 10.1038/nrrheum.2015.7. Epub 2015 Feb 10.

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.在亚洲和欧洲人群中，抗环瓜氨酸肽抗体（ACPA）阳性类风湿性关节炎的风险是由共享的人类白细胞抗原（HLA）氨基酸多态性驱动的。

Hum Mol Genet. 2014 Dec 20;23(25):6916-26. doi: 10.1093/hmg/ddu387. Epub 2014 Jul 28.

ACPA-negative RA consists of two genetically distinct subsets based on RF positivity in Japanese.ACPA 阴性 RA 包括两个基于日本人群 RF 阳性的遗传上不同的亚群。

PLoS One. 2012;7(7):e40067. doi: 10.1371/journal.pone.0040067. Epub 2012 Jul 6.

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HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.

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