Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA.
Psychosomatics. 2009 Sep-Oct;50(5):433-9. doi: 10.1176/appi.psy.50.5.433.
Human immunodeficiency virus (HIV) disease is associated with bereavement and grief reactions brought about by the disease process itself and by the losses of loved ones.
The goal of this review is to assess the current literature regarding grief, HIV, and immunity.
The authors reviewed applicable articles retrieved from a MEDLINE literature search with the search terms "bereavement/HIV," "grief/HIV," and "immunity/grief/HIV."
Data continue to emerge that suggest a profound role for bereavement in mediating HIV illness and the need to effectively deal with bereavement issues.
Patients who experience maladaptive grief show more rapid losses of CD4 T-cells over time, even when controlling for age, health status, use of antiretrovirals, and illicit drug abuse. This immune dysfunction may be managed by a variety of psychotherapeutic techniques.
人类免疫缺陷病毒（HIV）疾病与疾病本身以及失去亲人所带来的丧亲和悲伤反应有关。
本综述的目的是评估有关悲伤、HIV 和免疫的现有文献。
作者通过检索 MEDLINE 文献，使用“丧亲/HIV”、“悲伤/HIV”和“免疫/悲伤/HIV”等检索词，回顾了适用的文章。
有数据不断表明，丧亲在介导 HIV 疾病方面起着深远的作用，因此需要有效地处理丧亲问题。
即使在控制年龄、健康状况、使用抗逆转录病毒药物和非法药物滥用等因素的情况下，经历适应不良悲伤的患者随着时间的推移，其 CD4 T 细胞的损失也会更快。这种免疫功能障碍可以通过各种心理治疗技术来管理。
