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免疫功能低下的类风湿关节炎患者感染非伤寒沙门氏菌导致的感染性腹主动脉瘤。

Infected abdominal aortic aneurysm caused by nontyphoid Salmonella in an immunocompromised patient with rheumatoid arthritis.

机构信息

Department of Medicine and Rheumatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8519, Japan.

出版信息

J Infect Chemother. 2009 Oct;15(5):312-5. doi: 10.1007/s10156-009-0699-3. Epub 2009 Oct 24.

DOI:10.1007/s10156-009-0699-3
PMID:19856069
Abstract

Nontyphoid Salmonella strains are important pathogens commonly found worldwide, typically causing gastrointestinal illness. Here, we report a case of a 66-yearold man with an abdominal aortic infected (or so-called mycotic) aneurysm caused by Salmonella enterica subsp. enterica serovar Enteritidis (S. Enteritidis). He had multiple risk factors for atherosclerosis: age over 60, a long history of smoking, an 8-year history of diabetes mellitus, and a 10-year history of rheumatoid arthritis treated with low-dose corticosteroids. Although he had presented with no episode of diarrhea or abdominal pain, the abdominal aortic infected aneurysm was diagnosed by blood cultures and was carefully followed up by computed tomography. An abdominal aneurysmectomy and autogenous in situ reconstruction were successfully performed consequently. Alertness to the possibility of endovascular infection is important, even if there are no symptoms except for persistent fever, when treating Salmonella bacteremia in an immunocompromised patient, particularly when there are associated atherosclerotic risk factors.

摘要

非伤寒沙门氏菌菌株是一种常见的全球重要病原体,通常会导致胃肠道疾病。在这里,我们报告了一例由肠炎沙门氏菌亚种肠炎血清型(肠炎沙门氏菌)引起的 66 岁男性腹主动脉感染(或所谓的感染性)动脉瘤的病例。他有多个动脉粥样硬化的危险因素:年龄超过 60 岁、长期吸烟史、8 年糖尿病史和 10 年类风湿关节炎史,用小剂量皮质类固醇治疗。尽管他没有出现腹泻或腹痛,但通过血液培养诊断出腹主动脉感染性动脉瘤,并通过计算机断层扫描进行了仔细的随访。随后成功地进行了腹主动脉瘤切除术和自体原位重建。在治疗免疫功能低下患者的沙门氏菌菌血症时,即使除持续发热外没有任何症状,也需要警惕血管内感染的可能性,特别是当存在相关动脉粥样硬化危险因素时。

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引用本文的文献

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Mycotic Thoracic Aortic Aneurysm: Epidemiology, Pathophysiology, Diagnosis, and Management.真菌性胸主动脉瘤:流行病学、病理生理学、诊断与治疗
Cureus. 2022 Nov 2;14(11):e31010. doi: 10.7759/cureus.31010. eCollection 2022 Nov.
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Nontyphoid Salmonella-infected mycotic aneurysm in a patient with rheumatoid arthritis.
Rheumatol Int. 2013 Dec;33(12):3103-4. doi: 10.1007/s00296-012-2544-8. Epub 2012 Nov 5.