Henderson B E, Louie E W, Jing J S, Alena B
J Natl Cancer Inst. 1977 Nov;59(5):1393-5. doi: 10.1093/jnci/59.5.1393.
Antibody titers to all the Epstein-Barr virus (EBV)-related antigens were significant elevated (P less than 0.001) in patients with nasopharyngeal carcinoma (NPC) compared with those of controls. EBV, early antigen, and anti-diffuse titers of Chinese-American and black patients with NPC were higher than those of white patients with NPC. Epstein-Barr viral capsid antigen antibody titers were elevated in white patients with squamous cell carcinoma of the pharynx, regardless of subsite. These results raise doubts about the specificity of the association between EBV and NPC.
与对照组相比，鼻咽癌（NPC）患者针对所有爱泼斯坦-巴尔病毒（EBV）相关抗原的抗体滴度显著升高（P<0.001）。华裔美国人和黑人NPC患者的EBV、早期抗原及抗弥散抗体滴度高于白人NPC患者。无论病变部位如何，白人咽鳞状细胞癌患者的爱泼斯坦-巴尔病毒衣壳抗原抗体滴度均升高。这些结果对EBV与NPC之间关联的特异性提出了质疑。
