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对疑似局部复发性胃癌患者进行旨在治愈的剖腹手术。

Laparotomy with a curative intent in patients with suspected locally recurrent gastric cancer.

作者信息

Ozer Ilter, Bostanci E Birol, Ozogul Yusuf, Ulas Murat, Ercan Metin, Kece Can, Orug Taner, Atalay Fuat, Akoglu Musa

机构信息

Department of Gastrointestinal Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.

出版信息

Tumori. 2009 Jul-Aug;95(4):438-41. doi: 10.1177/030089160909500405.

DOI:10.1177/030089160909500405
PMID:19856653
Abstract

AIMS AND BACKGROUND

Most recurrent gastric tumors are unsuitable for further resection or palliative surgery. The aim of the present study was to evaluate the role of re-resection in patients with local-regional recurrences of gastric cancer.

METHODS AND STUDY DESIGN

Between 1998 and 2007, 26 patients underwent laparotomy for local-regional gastric cancer recurrence. Length of time to recurrence, recurrence patterns, operative procedures, morbidity, mortality and survival after re-resection were evaluated.

RESULTS

Re-resection was possible in 13 patients (50%). Among patients with resectable tumors, survival times were markedly longer, with 2 patients reaching 60 months of survival and 2 other patients reaching 48 and 28 months, respectively. Among patients with early recurrence, peritoneal carcinomatosis was more common. After re-resection, morbidity and mortality were seen, each in one patient.

CONCLUSIONS

Most of the re-resected recurrences were intraluminal. In patients with early recurrences of gastric cancer, peritoneal carcinomatosis was encountered most frequently. Re-resection was beneficial and long-term survival was achieved after re-resection.

摘要

目的与背景

大多数复发性胃肿瘤不适合进一步切除或姑息性手术。本研究的目的是评估再次切除在局部区域复发性胃癌患者中的作用。

方法与研究设计

1998年至2007年间,26例患者因局部区域胃癌复发接受了剖腹手术。评估了复发时间、复发模式、手术操作、发病率、死亡率及再次切除后的生存率。

结果

13例患者(50%)可行再次切除。在可切除肿瘤的患者中,生存时间明显更长,2例患者存活达60个月,另外2例患者分别存活达48个月和28个月。在早期复发的患者中,腹膜癌转移更为常见。再次切除后,各有1例患者出现了发病率和死亡率情况。

结论

大多数再次切除的复发灶位于腔内。在胃癌早期复发的患者中,腹膜癌转移最为常见。再次切除是有益的,再次切除后可实现长期生存。

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