针对多发性骨髓瘤患者的椎体后凸成形术是一种安全的外科手术：来自大型患者队列的结果。
Kyphoplasty for patients with multiple myeloma is a safe surgical procedure: results from a large patient cohort.
作者信息
Huber Franz-Xaver, McArthur Nicholas, Tanner Michael, Gritzbach Bernd, Schoierer Oliver, Rothfischer Wolfram, Krohmer Gerhard, Lessl Erich, Baier Martin, Meeder Peter Jürgen, Kasperk Christian
机构信息
Division of Traumatology and Reconstructive Surgery, Surgical Clinic, University of Heidelberg, Germany.
出版信息
Clin Lymphoma Myeloma. 2009 Oct;9(5):375-80. doi: 10.3816/CLM.2009.n.073.
INTRODUCTION
Only in recent years has balloon kyphoplasty gained significance in the treatment of vertebral fractures as an adequate minimally invasive vertebral stabilization technique. Kyphoplasty has also increasingly been used to treat vertebral osteolyses caused by multiple myeloma (MM).
PATIENTS AND METHODS
In our cohort of 76 patients with MM with a total of 190 vertebral fractures treated with kyphoplasty, we performed a 30-day postoperative analysis of cement leakage, neurologic symptoms, pulmonary embolism, and infections.
RESULTS
Painful osteolytic or fractured vertebrae or even imminent vertebral instability caused by osteolyses were seen as indications for kyphoplasty. One case of pulmonary embolism was observed because of cement leakage as the only postoperative complication.
CONCLUSION
By careful interdisciplinary indication setting and a standardized treatment model, kyphoplasty presents a very safe and effective procedure for the treatment of vertebral osteolyses and fractures caused by MM.
引言
仅在近年来，球囊后凸成形术作为一种合适的微创椎体稳定技术，在椎体骨折治疗中才具有重要意义。后凸成形术也越来越多地用于治疗由多发性骨髓瘤（MM）引起的椎体骨质溶解。
患者与方法
在我们的76例接受后凸成形术治疗的MM患者队列中，共有190处椎体骨折，我们对骨水泥渗漏、神经症状、肺栓塞和感染进行了术后30天分析。
结果
疼痛性骨质溶解或骨折椎体，甚至因骨质溶解导致的即将发生的椎体不稳定，被视为后凸成形术的指征。观察到1例因骨水泥渗漏导致的肺栓塞，这是唯一的术后并发症。
结论
通过谨慎的多学科指征设定和标准化治疗模式，后凸成形术是治疗MM引起的椎体骨质溶解和骨折的一种非常安全有效的方法。
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