卡马西平诱导的抗核抗体和系统性红斑狼疮样综合征。

Carbamazepine-induced antinuclear antibodies and systemic lupus erythematosus-like syndrome.

作者信息

De Giorgio C M, Rabinowicz A L, Olivas R D

机构信息

Department of Neurology, University of Southern California School of Medicine, Los Angeles 90033.

出版信息

Epilepsia. 1991 Jan-Feb;32(1):128-9. doi: 10.1111/j.1528-1157.1991.tb05623.x.

DOI:10.1111/j.1528-1157.1991.tb05623.x

PMID:1985821

Abstract

A 20-year-old woman developed a systemic lupus erythematosus (SLE)-like syndrome and a positive antinuclear antibody (ANA) soon after initiation of carbamazepine (CBZ) therapy. Symptoms and serology became normal after CBZ was discontinued. CBZ-induced SLE is an important but underecognized phenomenon.

摘要

一名20岁女性在开始服用卡马西平（CBZ）治疗后不久出现了系统性红斑狼疮（SLE）样综合征和抗核抗体（ANA）阳性。停用CBZ后，症状和血清学检查恢复正常。CBZ诱发的SLE是一种重要但未得到充分认识的现象。