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开发治疗脆弱的新方法。

Developing novel therapeutic approaches to frailty.

机构信息

Division of Geriatric Medicine, Saint Louis University School of Medicine and GRECC, VA Medical Center, St. Louis, Missouri 63104, USA.

出版信息

Curr Pharm Des. 2009;15(29):3384-95. doi: 10.2174/138161209789105045.

DOI:10.2174/138161209789105045
PMID:19860686
Abstract

Frailty is now defined as a clinical entity and potentially responsive to medications. This article reviews the drugs available and those under development. While, at present, exercise is the primary therapy, it is expected over the next decade that numerous drugs will be available to treat components of the frailty syndrome.

摘要

衰弱目前被定义为一种临床实体,可能对药物有反应。本文综述了现有的和正在开发的药物。虽然目前运动是主要的治疗方法,但预计在未来十年内,将有许多药物可用于治疗衰弱综合征的各个组成部分。

相似文献

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Developing novel therapeutic approaches to frailty.开发治疗脆弱的新方法。
Curr Pharm Des. 2009;15(29):3384-95. doi: 10.2174/138161209789105045.
2
Weight loss in older persons: new therapeutic approaches.老年人的体重减轻:新的治疗方法。
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The aging population--is there a role for endocrine interventions?老龄化人口——内分泌干预能发挥作用吗?
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Sarcopenia.肌肉减少症
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Essential steps in primary care management of older people with Type 2 diabetes: an executive summary on behalf of the European geriatric medicine society (EuGMS) and the European diabetes working party for older people (EDWPOP) collaboration.老年人 2 型糖尿病初级保健管理的基本步骤:代表欧洲老年医学学会(EuGMS)和欧洲老年人糖尿病工作组(EDWPOP)合作的执行摘要。
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Association of SARC-F Score and Rockwood Clinical Frailty Scale with CT-Derived Muscle Mass in Patients with Aortic Aneurysms.
SARC-F 评分和 Rockwood 临床虚弱量表与主动脉瘤患者 CT 衍生肌肉量的相关性。
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An Association between Lower Extremity Function and Cognitive Frailty: A Sample Population from the KFACS Study.下肢功能与认知衰弱的关联:来自 KFACS 研究的样本人群。
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Investigation of a possible association of potentially inappropriate medication for older adults and frailty in a prospective cohort study from Germany.一项来自德国的前瞻性队列研究调查了老年人潜在不适当药物与虚弱之间的可能关联。
Age Ageing. 2019 Dec 1;49(1):20-25. doi: 10.1093/ageing/afz127.
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FRAILTOOLS study protocol: a comprehensive validation of frailty assessment tools to screen and diagnose frailty in different clinical and social settings and to provide instruments for integrated care in older adults.FRAILTOOLS 研究方案:全面验证虚弱评估工具,以在不同临床和社会环境中筛查和诊断虚弱,并为老年人的综合护理提供工具。
BMC Geriatr. 2019 Mar 18;19(1):86. doi: 10.1186/s12877-019-1042-1.
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The Impact of Comorbidities on the Pharmacological Management of Type 2 Diabetes Mellitus.共病对 2 型糖尿病药物治疗管理的影响。
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