Fernando S Deepika, Abeyasinghe Rabindra R, Galappaththy Gawrie N L, Rajapaksa Lalani C
Department of Parasitology, Colombo, Sri Lanka.
Am J Trop Med Hyg. 2009 Nov;81(5):763-7. doi: 10.4269/ajtmh.2009.09-0042.
As the goal of malaria elimination from Sri Lanka is currently being pursued, this study was planned to determine the prevalence of asymptomatic malaria infections. Five health areas in Trincomalee and Kurunegala districts that reported high prevalence in the recent past were purposively selected. The smallest administrative units (GN divisions) having high malaria risk within each area were identified. From these divisions, 20% of the population was randomly selected for blood smear examination and in a 50% sub-sample polymerase chain reaction (PCR) assay was performed. A population of 3,730 from 13 GN divisions was sampled. Thick and thin Giemsa-stained blood smears were negative for malaria parasites. The PCR carried out in 50% of the study sample was also negative for malaria parasites. The findings illustrate the absence of asymptomatic carriers in previously high transmission areas and it appears that achieving malaria elimination in Sri Lanka by 2015 is feasible.
由于目前正在追求在斯里兰卡消除疟疾的目标，本研究旨在确定无症状疟疾感染的流行情况。故意选择了亭可马里和库鲁内格勒地区最近报告患病率较高的五个卫生区域。确定了每个区域内疟疾风险高的最小行政单位（GN分区）。从这些分区中，随机选择20%的人口进行血涂片检查，并对50%的子样本进行聚合酶链反应（PCR）检测。对来自13个GN分区的3730人进行了抽样。厚、薄吉姆萨染色血涂片疟原虫均为阴性。在50%的研究样本中进行的PCR检测疟原虫也为阴性。这些发现表明以前高传播地区不存在无症状携带者，看来在2015年前在斯里兰卡实现消除疟疾是可行的。
